Evidence map›Paper›PMID 39149041›Full record

ArticleHeliyon2024

An engineered lactate oxidase based electrochemical sensor for continuous detection of biomarker lactic acid in human sweat and serum.

Qingrong He, Cheng Wang, Rohit Jain, James Byrnes, Erik R Farquhar, Elliot Reed, Elizabeth Berezovsky, Mark R Chance, David Lodowski, Ran An

Abstract read
In one paragraph

Article in Heliyon, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Qingrong HeDepartment of Biomedical Engineering, University of Houston, United States.
Cheng WangDepartment of Biomedical Engineering, University of Houston, United States.
Rohit JainBiomolecular Structure and Integration of Sensors (BioSIS) Program, Department of Nutrition, School of Medicine, Case Western Reserve University, United States.
James ByrnesNational Synchrotron Light Source II, Brookhaven National Laboratory, United States.
Erik R FarquharBiomolecular Structure and Integration of Sensors (BioSIS) Program, Department of Nutrition, School of Medicine, Case Western Reserve University, United States.
Elliot ReedBiomolecular Structure and Integration of Sensors (BioSIS) Program, Department of Nutrition, School of Medicine, Case Western Reserve University, United States.
Elizabeth BerezovskyBiomolecular Structure and Integration of Sensors (BioSIS) Program, Department of Nutrition, School of Medicine, Case Western Reserve University, United States.
Mark R ChanceBiomolecular Structure and Integration of Sensors (BioSIS) Program, Department of Nutrition, School of Medicine, Case Western Reserve University, United States.
David LodowskiBiomolecular Structure and Integration of Sensors (BioSIS) Program, Department of Nutrition, School of Medicine, Case Western Reserve University, United States.
Ran AnDepartment of Biomedical Engineering, University of Houston, United States.

Funding

X-ray Scattering Technology CoreP30GM133893 · NIGMS · BROOKHAVEN SCIENCE ASSOC-BROOKHAVEN LAB · PI Vivian Stojanoff · 2019 to 2026
$38.6M
User Training and OutreachP30GM124165 · NIGMS · CORNELL UNIVERSITY · PI STEVEN E EALICK · 2018 to 2026
$34.2M
Multiplex labeling chemistry methods for protein footprintingR01GM141078 · NIGMS · CASE WESTERN RESERVE UNIVERSITY · PI KISELAR, JANNA · 2021 to 2024
$1.6M
A Simultaneous SAXS/WAXS Detector System for Solving Biological StructuresS10OD012331 · OD · STATE UNIVERSITY NEW YORK STONY BROOK · PI ALLAIRE, MARC · 2012 to 2012
$1.1M
Orbitrap Fusion Lumos Tribrid Mass SpectrometerS10OD026882 · OD · CASE WESTERN RESERVE UNIVERSITY · PI CHANCE, MARK R · 2019 to 2019
$1.0M
Q Exactive HF-X hybrid quadrupole-Orbitrap mass spectrometer (QE HF-X)S10OD028614 · OD · CASE WESTERN RESERVE UNIVERSITY · PI CHANCE, MARK R · 2020 to 2020
$600k
Roles of Red Blood Cell Derived Extracellular Vesicles in Complement Activation and Thromboinflammation in Sickle Cell DiseaseK25HL159358 · NHLBI · UNIVERSITY OF HOUSTON · PI Ran An · 2022 to 2026
$532k
NHLBI NIH HHS K25 HL159358NIGMS NIH HHS P30 GM124165NIGMS NIH HHS P30 GM133893NIGMS NIH HHS R01 GM141078NIH HHS S10 OD012331NIH HHS S10 OD026882NIH HHS S10 OD028614
6 · The paper itself

Abstract

Lactate levels in humans reveal intensity and duration of exertion and provide a critical readout for the severity of life-threatening illnesses such as pediatric sepsis. Using the lactate oxidase enzyme (Lox) from

Identifiers

PMID39149041
PMCPMC11324829

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.