Evidence map›Paper›PMID 39148559›Full record

ArticleCase reports in dentistry2024

Development of Root Caries Associated With the Use of Sugar-Free Nicotine Lozenges: A Long-Term Case Report.

Coral Ehrhardt, Kauko K Mäkinen, Charles M Cobb

Abstract readCase Reports
In one paragraph

Article in Case reports in dentistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Coral EhrhardtMoellers & Moellers Family Dentistry, 511 W Water St, Suite C, Decorah, Iowa 52101, USA.ORCID https://orcid.org/0009-0002-6982-4617
Kauko K MäkinenInstitute of Dentistry University of Turku, FI-20014 Turun yliopisto, Turku, Finland.ORCID https://orcid.org/0000-0003-1284-5126
Charles M CobbDepartment of Periodontics School of Dentistry University of Missouri-Kansas City, 650 E. 25th Street, Kansas City, Missouri 64108, USA.ORCID https://orcid.org/0000-0003-0844-2738

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The authors present a case concerning an adult male patient who developed multiple sites of root caries adjacent to the area where he habitually held a sugar-free nicotine lozenge that contained mannitol and maltodextrin. The root caries occurred despite the patient's excellent oral hygiene, exemplary dietary habits, and clinically normal salivary flow. Between 1999 and 2008, he had only required two restorations to repair carious lesions. This patient had a 20+-year habit of using smokeless tobacco before switching to a cessation aid nicotine lozenge in May of 2008. A full-mouth series of radiographs taken in November 2009 revealed carious lesions on virtually every posterior tooth. The nicotine lozenge's principal ingredients were mannitol (75.7%) and maltodextrin. According to the United States' current Food and Drug Administration (FDA) guidelines, manufacturers can advertise these lozenges as sugar-free. Thus, it is assumed by the public that these types of products are incapable of "causing a cavity." However, this case report presents evidence suggesting that frequent use of sugar-free nicotine lozenges may be associated with dental caries.

Indexed as

dental carieslozengemaltodextrinmannitolroot cariessugar alcoholstobacco cessation aids

Identifiers

PMID39148559
PMCPMC11325015

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.