ArticlePlastic and reconstructive surgery. Global open2024
Comparative Rheology of Hyaluronic Acid Fillers, Poly-l-lactic Acid, and Varying Dilutions of Calcium Hydroxylapatite.
Article in Plastic and reconstructive surgery. Global open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed.
- Morphological and Rheological Analysis of an Injectable Calcium Hydroxylapatite Dermal Filler with Lattice-Pore Surface Architecture.Journal of functional biomaterials · 2026Article
- Review
- Steady and Dynamic Rheological Properties of Concentrated Chitosan Solutions at Different Concentrations and Temperatures.Polymers · 2026Article
- Reconsidering the Biomechanical Basis of the V-Lift Technique with Calcium Hydroxyapatite.Aesthetic plastic surgery · 2026Article
- Expert Panel Guidelines for Hybrid CaHA-CMC/CPM-HA Fillers in the Mexican Population.Journal of cosmetic dermatology · 2025Article
- Exploring the Rheology and Clinical Potential of Calcium Hydroxylapatite-Hyaluronic Acid Hybrids.Journal of cosmetic dermatology · 2025Article
- Minimally Invasive Facial Lifting Using the Versatility of Calcium Hydroxyapatite (STIIM).Journal of cosmetic dermatology · 2025Article
- Treatment of the Temples: Brazilian Consensus.Aesthetic plastic surgery · 2025Article
- Dual Benefits of Calcium Hydroxyapatite Filler: A Prospective Study on Midface Volume Restoration and Skin Quality Enhancement.Journal of cosmetic dermatology · 2025Article
- Arterioembolic Characteristics of Differentially Diluted CaHA-CMC Gels Within An Artificial Macrovascular Perfusion Model.Aesthetic surgery journal · 2025Article
- Reply: Comparative Rheology of Hyaluronic Acid Fillers, Poly-l-lactic Acid, and Varying Dilutions of Calcium Hydroxylapatite.Plastic and reconstructive surgery. Global open · 2025Article
- Comparative Rheology of Hyaluronic Acid Fillers, Poly-l-lactic Acid, and Varying Dilutions of Calcium Hydroxylapatite.Plastic and reconstructive surgery. Global open · 2025Article
- A Randomized Clinical Trial Comparing Pure Hyaluronic Acid to the Hyaluronic Acid-Calcium Hydroxylapatite Combination for Temporal Volumization.Aesthetic surgery journal. Open forum · 2025Article
- Modulating rheology and bioactivity in dermal fillers: the emerging role of platelet-rich plasma (PRP).Frontiers in medicine · 2025Review
- Differentiating the Dilutional Rheology of Radiesse, Radiesse (+), and Radiesse With 0.26 mL of Lidocaine.Journal of cosmetic dermatology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: This study examines the rheological properties of various dermal fillers, including hyaluronic acid (HA) fillers, poly-L-lactic acid (PLLA), and calcium hydroxylapatite-carboxymethylcellulose (CaHA-CMC) gels, with a particular focus on the impact of aqueous dilution on CaHA-CMC's rheology and potential clinical implications. Methods: Using standardized rheological analysis, we measured and compared the elastic modulus (G'), viscous modulus (G″), and the tan δ values of different dilutions of CaHA-CMC against published values of HA and PLLA fillers. The study aimed to determine the potential clinical use of application-specific CaHA-CMC hydrogel dilutions along a range of gel strength and cohesion for hydrogel fillers in current use. Results: The findings demonstrate that CaHA-CMC's rheological properties can be tailored across a broad spectrum of viscoelastic parameters through titrated dilution, ranging from high elasticity to low cohesion. Varying the aqueous volume allows for the rheomodulation of CaHA-CMC, potentially matching the entire rheological spectrum of HA fillers and suggesting an expanded range of clinical applications. Conclusions: The versatility of CaHA-CMC through dilution may offer a customizable approach for clinical applications, providing practitioners with the ability to fine-tune the properties of fillers to meet specific patient needs and treatment goals. This study lays the groundwork for the potential future use of filler dilutional rheomodulation in clinical practice, tailored to patient- and application-specific needs.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.