Evidence map›Paper›PMID 39148439›Full record

ArticleTherapeutic advances in respiratory disease

Diagnostic value of serum vascular endothelial growth factor-D in Korean patients with lymphangioleiomyomatosis.

Hee-Young Yoon, Su-Jin Moon, Song Yee Kim, Jong Sun Park, Sun Mi Choi, Hyung Koo Kang, Jin Woo Song

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Therapeutic advances in respiratory disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Hee-Young YoonDivision of Allergy and Respiratory Diseases, Soonchunhyang University Seoul Hospital, Seoul, Republic of Korea.
Su-Jin MoonDepartment of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Song Yee KimDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Yonsei University College of Medicine, Severance Hospital, Seoul, Republic of Korea.
Jong Sun ParkDepartment of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam-si, Republic of Korea.
Sun Mi ChoiDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Seoul National University College of Medicine, Seoul National University Hospital, Seoul, Republic of Korea.ORCID 0000-0002-0742-6085
Hyung Koo KangDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Inje University Ilsan Paik Hospital, Goyang, Republic of Korea.
Jin Woo SongDepartment of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-Ro 43-Gil, Songpa-Gu, Seoul 05505, Republic of Korea.ORCID 0000-0001-5121-3522

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLymphangioleiomyomatosis (LAM) is a rare multisystemic disorder characterized by the proliferation of abnormal smooth muscle-like cells. Although serum vascular endothelial growth factor-D (VEGF-D) is currently used as a diagnostic biomarker for LAM, its diagnostic value in Korean patients is unclear.

objectivesTo evaluate the diagnostic value of serum VEGF-D for LAM in Korean patients.

designA multicenter prospective cohort study.

methodsSerum samples were prospectively collected from five medical institutions, from patients with LAM (

resultsThe mean age of patients with LAM was 44.5 years, and all were female (controls: 47.8 years; female: 70.8%,

conclusionOur results suggest that serum VEGF-D may be a useful biomarker for diagnosing LAM in Korean patients, similar to previous reports.

Indexed as

Enzyme-Linked Immunosorbent AssayLymphangioleiomyomatosisVascular Endothelial Growth Factor DAdultBiomarkersCase-Control StudiesCohort StudiesFemaleHumansLung NeoplasmsMaleMiddle AgedPredictive Value of TestsProspective StudiesRepublic of KoreaROC CurveBiomarkersVascular Endothelial Growth Factor DVEGFD protein, humanbiomarkerdiagnosislymphangioleiomyomatosisrare lung diseasevascular endothelial growth factor-D

Identifiers

PMID39148439
PMCPMC11329922

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