Evidence map›Paper›PMID 39148094›Full record

ArticleImplementation science : IS2024

Reducing asthma attacks in disadvantaged school children with asthma: study protocol for a type 2 hybrid implementation-effectiveness trial (Better Asthma Control for Kids, BACK).

Amy G Huebschmann, Nicole M Wagner, Melanie Gleason, John T Brinton, Michaela Brtnikova, Sarah E Brewer, Anowara Begum, Rachel Armstrong, Lisa Ross DeCamp, Arthur McFarlane and 5 more

Registry-linked trialAbstract readClinical Trial Protocol
In one paragraph

Article in Implementation science : IS, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06003569 (Reducing Asthma Attacks in Disadvantaged School Children With Asthma), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06003569 narecruitingnot on this map

Reducing Asthma Attacks in Disadvantaged School Children With Asthma

TypeinterventionalSponsorUniversity of Colorado, DenverRan2023 to 2027Enrolled300ConditionsAsthma in ChildrenArmsBACK-S, BACK-E
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Amy G HuebschmannAnschutz Medical Campus Department of Medicine, Division of General Internal Medicine, University of Colorado, 12631 E. 17th Ave., Mailstop B180, Aurora, CO, USA. amy.huebschmann@ucdenver.edu.ORCID 0000-0002-9329-3142
Nicole M WagnerAnschutz Medical Campus Department of Medicine, Division of General Internal Medicine, University of Colorado, 12631 E. 17th Ave., Mailstop B180, Aurora, CO, USA.
Melanie GleasonDepartment of Pediatrics, University of Colorado School of Medicine, Aurora, USA, CO.
John T BrintonDepartment of Pediatrics, University of Colorado School of Medicine, Aurora, USA, CO.
Michaela BrtnikovaAdult and Child Center for Outcomes Research and Delivery Science (ACCORDS), 1890 Revere Ct, Suite P32-3200, Mailstop F443, Aurora, CO, 80045, USA.
Sarah E BrewerAdult and Child Center for Outcomes Research and Delivery Science (ACCORDS), 1890 Revere Ct, Suite P32-3200, Mailstop F443, Aurora, CO, 80045, USA.
Anowara BegumAdult and Child Center for Outcomes Research and Delivery Science (ACCORDS), 1890 Revere Ct, Suite P32-3200, Mailstop F443, Aurora, CO, 80045, USA.
Rachel ArmstrongAdult and Child Center for Outcomes Research and Delivery Science (ACCORDS), 1890 Revere Ct, Suite P32-3200, Mailstop F443, Aurora, CO, 80045, USA.
Lisa Ross DeCampAdult and Child Center for Outcomes Research and Delivery Science (ACCORDS), 1890 Revere Ct, Suite P32-3200, Mailstop F443, Aurora, CO, 80045, USA.
Arthur McFarlaneBreathing Institute, Children's Hospital Colorado, 13123 East 16Th Avenue, Mailstop B395, Aurora, CO, 80045, USA.
Heather DeKeyserAdult and Child Center for Outcomes Research and Delivery Science (ACCORDS), 1890 Revere Ct, Suite P32-3200, Mailstop F443, Aurora, CO, 80045, USA.
Holly ColemanTrailhead Institute, 1999 Broadway Suite 200, Denver, CO, 80202, USA.
Monica J FedericoDepartment of Pediatrics, University of Colorado School of Medicine, Aurora, USA, CO.
Stanley J SzeflerDepartment of Pediatrics, University of Colorado School of Medicine, Aurora, USA, CO.
Lisa C CicuttoNational Jewish Health and University of Colorado College of Nursing and Clinical Sciences, Aurora, CO, USA.

Funding

Reducing Asthma Attacks in Disadvantaged School Children with AsthmaUH3HL151297 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI Lisa Cicutto, Amy Grotelueschen Huebschmann · 2023 to 2026
$4.1M
Reducing Asthma Attacks in Disadvantaged School Children with AsthmaUG3HL151297 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI CICUTTO, LISA, HUEBSCHMANN, AMY GROTELUESCHEN · 2020 to 2022
$2.9M
CTSA Predoctoral T32 at University of Colorado DenverT32TR004367 · NCATS · UNIVERSITY OF COLORADO DENVER · PI Lisa Cicutto · 2023 to 2026
$1.5M
Treatment Phenotypes for Adolescents with AsthmaK23HL146791 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI DE KEYSER, HEATHER · 2020 to 2024
$837k
Vending machine Naloxone Distribution for Your community (VENDY): Increasing reach and implementation of naloxone distributionK01DA056698 · NIDA · UNIVERSITY OF COLORADO DENVER · PI WAGNER, NICOLE MARIE · 2022 to 2025
$616k
Colorado Department of Public Health and Environment Expansion 2024*0346NCATS NIH HHS T32 TR004367NHLBI NIH HHS K23 HL146791NHLBI NIH HHS K23HL146791NHLBI NIH HHS UG3 HL151297NHLBI NIH HHS UG3HL151297NHLBI NIH HHS UH3 HL151297NHLBI NIH HHS UH3HL151297NIDA NIH HHS K01 DA056698NIDA NIH HHS K01DA056698
6 · The paper itself

Abstract

backgroundAsthma is a leading cause of children's hospitalizations, emergency department visits, and missed school days. Our school-based asthma intervention has reduced asthma exacerbations for children experiencing health disparities in the Denver Metropolitan Area, due partly to addressing care coordination for asthma and social determinants of health (SDOH), such as access to healthcare and medications. Limited dissemination of school-based asthma programs has occurred in other metropolitan and rural areas of Colorado. We formed and engaged community advisory boards in socioeconomically diverse regions of Colorado to develop two implementation strategy packages for delivering our school-based asthma intervention - now termed "Better Asthma Control for Kids (BACK)" - with tailoring to regional priorities, needs and resources.

methodsIn this proposed type 2 hybrid implementation-effectiveness trial, where the primary goal is equitable reach to families to reduce asthma disparities, we will compare two different packages of implementation strategies to deliver BACK across four Colorado regions. The two implementation packages to be compared are: 1) standard set of implementation strategies including Tailor and Adapt to context, Facilitation and Training termed, BACK-Standard (BACK-S); 2) BACK-S plus an enhanced implementation strategy, that incorporates network weaving with community partners and consumer engagement with school families, termed BACK-Enhanced (BACK-E). Our evaluation will be guided by the Reach, Effectiveness, Adoption, Implementation, and Maintenance (RE-AIM) framework, including its Pragmatic Robust Implementation Sustainability Model (PRISM) determinants of implementation outcomes. Our central hypothesis is that our BACK-E implementation strategy will have significantly greater reach to eligible children/families than BACK-S (primary outcome) and that both BACK-E and BACK-S groups will have significantly reduced asthma exacerbation rates ("attacks") and improved asthma control as compared to usual care. DISCUSSION: We expect both the BACK-S and BACK-E strategy packages will accelerate dissemination of our BACK program across the state - the comparative impact of BACK-S vs. BACK-E on reach and other RE-AIM outcomes may inform strategy selection for scaling BACK and other effective school-based programs to address chronic illness disparities.

trial registrationClinicaltrials.gov identifier: NCT06003569, registered on August 22, 2023, https://classic. CLINICALTRIALS: gov/ct2/show/NCT06003569 .

Indexed as

AsthmaSchool Health ServicesAdolescentChildColoradoFemaleHumansImplementation SciencePragmatic Clinical Trials as TopicVulnerable PopulationsAsthmaChild healthHealth equityImplementation scienceSchool health servicesSocial determinants of health

Identifiers

PMID39148094
PMCPMC11325631

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.