Evidence map›Paper›PMID 39147790›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2024

Blood product transfusion practices in neonates with hypoxic-ischemic encephalopathy.

Atiyeh A Miran, Michelle Stoopler, Mehmet Nevzat Cizmeci, Amr El Shahed, Rosanna Yankanah, Ashley Danguecan, Linh Ly, Marisa Signorile, Kyle Runeckles, Chun-Po Steve Fan and 1 more

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In one paragraph

Article in Journal of perinatology : official journal of the California Perinatal Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Atiyeh A MiranDivision of Neonatology, Department of Paediatrics, Hospital for Sick Children, Toronto, ON, M5G 1×8, Canada.
Michelle StooplerDepartment of Paediatrics, Hospital for Sick Children, Toronto, ON, M5G 1×8, Canada.
Mehmet Nevzat CizmeciDivision of Neonatology, Department of Paediatrics, Hospital for Sick Children, Toronto, ON, M5G 1×8, Canada.
Amr El ShahedDivision of Neonatology, Department of Paediatrics, Hospital for Sick Children, Toronto, ON, M5G 1×8, Canada.ORCID 0000-0002-5898-1927
Rosanna YankanahDivision of Neonatology, Department of Paediatrics, Hospital for Sick Children, Toronto, ON, M5G 1×8, Canada.
Ashley DanguecanDivision of Neonatology, Department of Paediatrics, Hospital for Sick Children, Toronto, ON, M5G 1×8, Canada.
Linh LyDivision of Neonatology, Department of Paediatrics, Hospital for Sick Children, Toronto, ON, M5G 1×8, Canada.
Marisa SignorileTed Rogers Computational Program, Peter Munk Cardiac Centre, University Health Network, 200 Elizabeth Street, Toronto, ON, M5G 2C4, Canada.
Kyle RunecklesTed Rogers Computational Program, Peter Munk Cardiac Centre, University Health Network, 200 Elizabeth Street, Toronto, ON, M5G 2C4, Canada.
Chun-Po Steve FanTed Rogers Computational Program, Peter Munk Cardiac Centre, University Health Network, 200 Elizabeth Street, Toronto, ON, M5G 2C4, Canada.ORCID 0000-0002-1278-0118
Brian T KalishDivision of Neonatology, Department of Paediatrics, Hospital for Sick Children, Toronto, ON, M5G 1×8, Canada. brian.kalish@sickkids.ca.ORCID 0000-0003-3235-6856

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveBlood product transfusion is a common practice in infants with hypoxic-ischemic encephalopathy (HIE) undoing therapeutic hypothermia (TH). The advantages and disadvantages of conservative or liberal transfusion practices in this fragile population are unknown. Study aims to characterize the transfusion practices in infants with HIE and investigate the association with outcome. STUDY

designWe conducted a retrospective cohort study at a single level IV NICU, evaluating transfusion thresholds, as well as the association between hematological abnormalities or blood product transfusions and outcomes in infants admitted with HIE.

resultBy univariate analysis, FFP transfusion was associated with increased in-hospital death. However, multivariate analysis adjusting for HIE severity demonstrated no association between hematological abnormality or blood product transfusion and death, nor with neurodevelopmental impairment.

conclusionNo association was found between hematological blood product transfusion and death or neurodevelopmental impairment in a retrospective single NICU study of infants with HIE.

Indexed as

Hypoxia-Ischemia, BrainBlood TransfusionFemaleHospital MortalityHumansHypothermia, InducedInfant, NewbornIntensive Care Units, NeonatalMaleMultivariate AnalysisPlasmaRetrospective Studies

Identifiers

PMID39147790

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.