Evidence map›Paper›PMID 39147710›Full record

ReviewZhongguo fei ai za zhi = Chinese journal of lung cancer2024

[Progress of IL-21 and Tfh Mediated Immunotherapy in Non-small Cell Lung Cancer].

Xingkai Liu, Yifan Zhang, Xin Zhang, Gonghao He, Wenke Cai

Abstract readReviewEnglish Abstract
In one paragraph

Review in Zhongguo fei ai za zhi = Chinese journal of lung cancer, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xingkai LiuDepartment of Cardiothoracic Surgery, 920th Hospital of Joint Logistic Support Force of the People's Liberation Army, Kunming 650032, China.
Yifan ZhangDepartment of Cardiothoracic Surgery, 920th Hospital of Joint Logistic Support Force of the People's Liberation Army, Kunming 650032, China.
Xin ZhangDepartment of Respiratory and Critical Care Medicine, 920th Hospital of Joint Logistic Support Force of the People's Liberation Army, Kunming 650032, China.
Gonghao HeDepartment of Clinical Pharmacy, 920th Hospital of Joint Logistic Support Force of the People's Liberation Army, Kunming 650032, China.
Wenke CaiDepartment of Cardiothoracic Surgery, 920th Hospital of Joint Logistic Support Force of the People's Liberation Army, Kunming 650032, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Non-small cell lung cancer (NSCLC) is a prevalent and aggressive global malignancy. Conventional surgical treatments, radiotherapy, chemotherapy, and targeted therapies often fall short in halting disease progression due to inherent limitations, resulting in suboptimal prognosis. Despite the advent of immunotherapy drugs offering new hope for NSCLC treatment, current efficacy remains insufficient to meet all patient needs. Therefore, actively exploring novel immunotherapeutic approaches to further reduce mortality rates in NSCLC patients has become a crucial focus of NSCLC research. This article aims to systematically review the anti-tumor effects of interleukin-21 and follicular helper T cells in NSCLC immunotherapy by summarizing and analyzing relevant literatures from both domestic and international sources, as well as exploring the potential for enhancing NSCLC treatment prospects through immune checkpoint regulation via immunotherapeutic means.
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Indexed as

Carcinoma, Non-Small-Cell LungImmunotherapyInterleukinsLung NeoplasmsAnimalsHumansInterleukin-21Interleukin-21InterleukinsFollicular helper T cellsImmune checkpoint proteinsInterleukin-21Lung neoplasms

Identifiers

PMID39147710
PMCPMC11331254

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.