Evidence map›Paper›PMID 39147399›Full record

SynthesisBMJ open respiratory research2024

Physical activity, sedentary behaviour, and childhood asthma: a European collaborative analysis.

Marianne Eijkemans, Monique Mommers, Margreet W Harskamp-van Ginkel, Tanja G M Vrijkotte, Johnny Ludvigsson, Åshild Faresjö, Anna Bergström, Sandra Ekström, Veit Grote, Berthold Koletzko and 41 more

Abstract readMeta-Analysis
In one paragraph

Synthesis in BMJ open respiratory research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Development of the Respiratory System During Adolescence.Advances in experimental medicine and biology · 2026
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

51 authors.

Marianne EijkemansMaastricht University Care and Public Health Research Institute, Maastricht, Netherlands m.eijkemans@alumni.maastrichtuniversity.nl.ORCID http://orcid.org/0000-0003-4550-8628
Monique MommersMaastricht University Care and Public Health Research Institute, Maastricht, Netherlands.ORCID http://orcid.org/0000-0002-6341-3596
Margreet W Harskamp-van GinkelDepartment of Public and Occupational Health, Amsterdam Public Health Research Institute, Amsterdam UMC Locatie Meibergdreef, Amsterdam, Netherlands.ORCID http://orcid.org/0000-0001-8792-6663
Tanja G M VrijkotteDepartment of Public and Occupational Health, Amsterdam Public Health Research Institute, Amsterdam UMC Locatie Meibergdreef, Amsterdam, Netherlands.ORCID http://orcid.org/0000-0003-3641-4048
Johnny LudvigssonDivision of Pediatrics, Department of Biomedical and Clinical Sciences (BKV), Medical Faculty, Crown Princess Victoria Children's Hospital, Linköping University Hospital, Linköping, Sweden.ORCID http://orcid.org/0000-0003-1695-5234
Åshild FaresjöDepartment of Health, Medicine and Caring Sciences; Public Health, Faculty of Medicine and Health Sciences, Linköping University, Linköping, Sweden.ORCID http://orcid.org/0000-0003-0723-139X
Anna BergströmInstitute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.ORCID http://orcid.org/0000-0002-7981-6314
Sandra EkströmInstitute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.ORCID http://orcid.org/0000-0002-2060-8190
Veit GroteDepartment of Pediatrics, Munich University Hospital Dr von Hauner Children's Hospital, Munchen, Germany.ORCID http://orcid.org/0000-0001-7168-2385
Berthold KoletzkoDepartment of Pediatrics, Munich University Hospital Dr von Hauner Children's Hospital, Munchen, Germany.ORCID http://orcid.org/0000-0002-5345-7165
Klaus BønnelykkeCopenhagen University Hospital, Gentofte, Copenhagen Prospective Studies on Asthma in Childhood, Copenhagen, Denmark.ORCID http://orcid.org/0000-0003-2003-1018
Anders Ulrik EliasenCopenhagen University Hospital, Gentofte, Copenhagen Prospective Studies on Asthma in Childhood, Copenhagen, Denmark.ORCID http://orcid.org/0000-0003-2629-0790
Peter BagerDepartment of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark.ORCID http://orcid.org/0000-0002-3577-8459
Mads MelbyeK.G. Jebsen Center for Genetic Epidemiology, Norwegian University of Science and Technology, Trondheim, Norway.ORCID http://orcid.org/0000-0001-8264-6785
Isabella Annesi-MaesanoInstitute Desbrest of Epidemiology and Public Health, University of Montpellier and INSERM, Montpellier, France.ORCID http://orcid.org/0000-0002-6340-9300
Nour BaïzInstitute Desbrest of Epidemiology and Public Health, University of Montpellier and INSERM, Montpellier, France.ORCID http://orcid.org/0000-0001-6165-3935
Henrique BarrosInstituto de Saúde Pública da Universidade do Porto, UP EPIUnit, Porto, Portugal.ORCID http://orcid.org/0000-0003-4699-6571
Ana Cristina SantosInstituto de Saúde Pública da Universidade do Porto, UP EPIUnit, Porto, Portugal.ORCID http://orcid.org/0000-0002-2992-5299
Liesbeth DuijtsThe Generation R Study Group, Erasmus Medical Center, Rotterdam, Netherlands.ORCID http://orcid.org/0000-0001-6731-9452
Sara M Mensink-BoutThe Generation R Study Group, Erasmus Medical Center, Rotterdam, Netherlands.ORCID http://orcid.org/0000-0002-5381-6287
Claudia FlexederGerman Research Center for Environmental Health, Institute of Epidemiology Helmholtz Zentrum München, Neuherberg, Germany.ORCID http://orcid.org/0000-0003-3974-1482
Sibylle KoletzkoDepartment of Pediatrics, Munich University Hospital Dr von Hauner Children's Hospital, Munchen, Germany.ORCID http://orcid.org/0000-0003-2374-8778
Tamara SchikowskiDepartment of Epidemiology, IUF Leibniz Research Institute for Environmental Medicine, Düsseldorf, Germany.ORCID http://orcid.org/0000-0002-4559-9374
Merete Åse EggesbøDepartment of Environmental Epidemiology, Norwegian Institute of Public Health, Oslo, Norway.ORCID http://orcid.org/0000-0002-0006-5336
Virissa LentersDepartment of Environmental Epidemiology, Norwegian Institute of Public Health, Oslo, Norway.ORCID http://orcid.org/0000-0002-0444-9150
Guillermo Fernández-TardónInstituto de Investigación Sanitaria del Principado de Asturias (ISPA), University of Oviedo, CIBERESP, Madrid, Spain.ORCID http://orcid.org/0000-0002-7680-158X
Mikel Subiza-PerezGroup of Environmental Epidemiology and Child Development, Biodonostia Health Research Institute, Donostia-san Sebastian, Spain.ORCID http://orcid.org/0000-0002-6843-8557
Judith Garcia-AymerichNon-Communicable Diseases and Environment Research Programme, Barcelona Institute for Global Health, Barcelona, Spain.ORCID http://orcid.org/0000-0002-7097-4586
Mónica López-VicenteISGlobal, Barcelona, Spain.ORCID http://orcid.org/0000-0002-5090-7538
Jordi SunyerSpanish Consortium for Research on Epidemiology and Public Health (CIBERESP), Instituto de Salud Carlos III, Madrid, Spain.ORCID http://orcid.org/0000-0002-2602-4110
Maties TorrentÀrea de Salut de Menorca, Menorca, Spain.ORCID http://orcid.org/0000-0001-8728-3741
Ferran BallesterSpanish Consortium for Research on Epidemiology and Public Health (CIBERESP), Instituto de Salud Carlos III, Madrid, Spain.ORCID http://orcid.org/0000-0002-6165-3465
Cecily KelleherUCD School of Public Health, Physiotherapy and Sports Science, College of Health and Agricultural Sciences, University College Dublin, Dublin, Ireland.ORCID http://orcid.org/0000-0001-9548-4914
John MeheganUCD School of Public Health, Physiotherapy and Sports Science, College of Health and Agricultural Sciences, University College Dublin, Dublin, Ireland.ORCID http://orcid.org/0000-0002-4229-3599
Andrea von BergResearch Institute, Department of Pediatrics, Marien-Hospital Wesel gGmbH, Wesel, Germany.ORCID http://orcid.org/0000-0003-0168-1541
Gunda HerberthDepartment of Environmental Immunology, Helmholtz-Centre for Environmental Research - UFZ, Leipzig, Germany.ORCID http://orcid.org/0000-0003-0212-3509
Marie StandlGerman Research Center for Environmental Health, Institute of Epidemiology Helmholtz Zentrum München, Neuherberg, Germany.ORCID http://orcid.org/0000-0002-5345-2049
Claudia E KuehniInstitute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.ORCID http://orcid.org/0000-0001-8957-2002
Eva S L PedersenInstitute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.ORCID http://orcid.org/0000-0003-0293-9954
Maria JansenPublic Health Services, Academic Collaborative Centre for Public Health Limburg, Heerlen, Netherlands.ORCID http://orcid.org/0000-0002-1843-139X
Ulrike GehringUtrecht University Institute for Risk Assessment Sciences, Utrecht, Netherlands.ORCID http://orcid.org/0000-0003-3612-5780
Jolanda M A BoerNational Institute for Public Health and the Environment, Bilthoven, Netherlands.ORCID http://orcid.org/0000-0002-9714-4304
Graham DevereuxDepartment of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK.ORCID http://orcid.org/0000-0002-0024-4887
Steve TurnerWomen and Children's Division, NHS Grampian, Aberdeen, UK.ORCID http://orcid.org/0000-0001-8393-5060
Ville PeltolaDepartment of Paediatrics and Adolescent Medicine, TYKS Turku University Hospital, Turku, Finland.ORCID http://orcid.org/0000-0003-3529-2747
Hanna LagströmDepartment of Public Health and Centre for Population Health Research, University of Turku, Turku, Finland.ORCID http://orcid.org/0000-0002-5069-6582
Hazel M InskipMRC Lifecourse Epidemiology Centre, University of Southampton, Southampton, UK.ORCID http://orcid.org/0000-0001-8897-1749
Katharine C PikeBristol Royal Hospital for Children, Bristol, UK.ORCID http://orcid.org/0000-0003-4911-6082
Geertje W DalmeijerJulius Center for Health Sciences and Primary Care, Utrecht, Netherlands.ORCID http://orcid.org/0000-0002-9048-6635
Cornelis K van der EntDepartment of Paediatric Pulmonology, Wilhelmina Children's Hospital University Medical Centre, Utrecht, Netherlands.
Carel ThijsMaastricht University Care and Public Health Research Institute, Maastricht, Netherlands.ORCID http://orcid.org/0000-0001-6646-5458

Funding

HSRD VA TPR 15-230
6 · The paper itself

Abstract

objectivesTo investigate the associations of physical activity (PA) and sedentary behaviour in early childhood with asthma and reduced lung function in later childhood within a large collaborative study.

designPooling of longitudinal data from collaborating birth cohorts using meta-analysis of separate cohort-specific estimates and analysis of individual participant data of all cohorts combined.

settingChildren aged 0-18 years from 26 European birth cohorts.

participants136 071 individual children from 26 cohorts, with information on PA and/or sedentary behaviour in early childhood and asthma assessment in later childhood.

main outcome measureQuestionnaire-based current asthma and lung function measured by spirometry (forced expiratory volume in 1 s (FEV

resultsQuestionnaire-based and accelerometry-based PA and sedentary behaviour at age 3-5 years was not associated with asthma at age 6-18 years (PA in hours/day adjusted OR 1.01, 95% CI 0.98 to 1.04; sedentary behaviour in hours/day adjusted OR 1.03, 95% CI 0.99 to 1.07). PA was not associated with lung function at any age. Analyses of sedentary behaviour and lung function showed inconsistent results.

conclusionsReduced PA and increased sedentary behaviour before 6 years of age were not associated with the presence of asthma later in childhood.

Indexed as

AsthmaExerciseSedentary BehaviorAccelerometryAdolescentBirth CohortChildChild, PreschoolEuropeFemaleForced Expiratory VolumeHumansInfantInfant, NewbornLongitudinal StudiesMaleAsthmaExercisePaediatric asthma

Identifiers

PMID39147399
PMCPMC11331876

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.