Evidence map›Paper›PMID 39147276›Full record

ArticleThe journal of allergy and clinical immunology. In practice2024

Neighborhood Deprivation and Crime on Asthma Exacerbations and Utilization in Mild Adult Asthma.

Stanley Xu, Eric J Puttock, Robert S Zeiger, William M Vollmer, Michael Schatz, William W Crawford, Fagen Xie, Wansu Chen

Abstract read
In one paragraph

Article in The journal of allergy and clinical immunology. In practice, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Managing childhood asthma with an eye toward environmental, social, and behavioral features.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Stanley XuDepartment of Research and Evaluation, Kaiser Permanente Southern California, Pasadena, Calif. Electronic address: Stan.Xu@kp.org.
Eric J PuttockDepartment of Research and Evaluation, Kaiser Permanente Southern California, Pasadena, Calif.
Robert S ZeigerDepartment of Allergy, Kaiser Permanente Southern California, San Diego, Calif; Department of Clinical Science, Kaiser Permanente Bernard J. Tyson School of Medicine, Pasadena, Calif.
William M VollmerKaiser Permanente Center for Health Research, Portland, Ore.
Michael SchatzDepartment of Allergy, Kaiser Permanente Southern California, San Diego, Calif; Department of Clinical Science, Kaiser Permanente Bernard J. Tyson School of Medicine, Pasadena, Calif.
William W CrawfordDepartment of Allergy, Kaiser Permanente Southern California, Harbor City, Calif.
Fagen XieDepartment of Research and Evaluation, Kaiser Permanente Southern California, Pasadena, Calif.
Wansu ChenDepartment of Research and Evaluation, Kaiser Permanente Southern California, Pasadena, Calif.

Funding

Predicting Exacerbations of Asthma in Real-World Patients with Low Medical Utilization (PEARL)R01HL163049 · NHLBI · KAISER FOUNDATION RESEARCH INSTITUTE · PI Wansu Chen · 2023 to 2026
$3.0M
NHLBI NIH HHS R01 HL163049
6 · The paper itself

Abstract

backgroundSocial determinants of health have a significant impact on asthma outcomes, and factors such as income level and neighborhood environment have crucial roles.

objectiveThis study aimed to assess the impact of the Neighborhood Deprivation Index (NDI) and Total Crime Index (TCI) on acute asthma exacerbation (AAE) and asthma-related emergency department and urgent care (ED/UC) visits in adults with mild asthma.

methodsThis retrospective cohort study used administrative data from Kaiser Permanente Southern California among 198,873 adult patients with mild asthma between January 1, 2013 and December 31, 2018. We employed robust Poisson regression models, adjusted for age and sex, to investigate the associations of NDI and TCI with AAE and asthma-related ED/UC visits. Data analysis included subgroup assessments by race and ethnicity and body mass index categories to explore potential disparities in asthma outcomes.

resultsAmong the cohort, 12,906 patients (6.5%) experienced AAE in 1 year, and Black patients had the highest AAE percentage (7.1%). Higher NDI quintiles were associated with increased AAE risk (adjusted risk ratio = 1.11-1.27), with similar trends across body mass index categories and race or ethnicity, except for Black patients. The TCI showed weaker associations with AAE. Regarding ED/UC visits, 5.0% had such visits within 1 year. Higher NDI quintiles were associated with higher ED/UC visit risk (adjusted risk ratio = 1.23-1.75) whereas TCI associations were weaker.

conclusionAddressing socioeconomic disparities, as indicated by NDI, may be crucial in mitigating asthma exacerbations and reducing health care use, highlighting the importance of incorporating social determinants into asthma management strategies even in patients with mild asthma.

Indexed as

AsthmaCrimeResidence CharacteristicsAdolescentAdultAgedCaliforniaDisease ProgressionEmergency Service, HospitalFemaleHumansMaleMiddle AgedRetrospective StudiesSocial Determinants of HealthSocioeconomic FactorsAcute asthma exacerbationHealth care useMild asthmaNeighborhood Deprivation IndexSocial determinants of healthTotal Crime Index

Identifiers

PMID39147276
PMCPMC11560689

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.