ArticleOptics letters2024
On-axis full-field swept-source optical coherence tomography for murine retinal imaging.
Article in Optics letters, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Coefficient-metric gradient-based digital wavefront correction for full-field swept-source optical coherence tomography.Biomedical optics express · 2026Article
- Computational framework for combining multiple swept-sources for high-resolution in-vivo optical coherence tomography.Biomedical optics express · 2026Article
- Rapid spectral shaping for time domain and swept source full field OCT.Biomedical optics express · 2025Article
- Combined optical coherence tomography and electroretinography system for imaging neurovascular coupling in the human retina.Neurophotonics · 2025Article
- Phase-restoring subpixel image registration: enhancing motion detection performance in Fourier-domain optical coherence tomography.Journal of physics D: Applied physics · 2025Article
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Authors and funding
6 authors.
Funding
Abstract
A full-field swept-source optical coherence tomography (FF-SS-OCT) for in vivo murine retinal imaging is demonstrated. The on-axis FF-SS-OCT system was built in a Mach-Zehnder interferometer configuration employing a tunable laser source with an adjustable sweep rate and sweep range in conjunction with a fast 2D-CMOS camera. A large field retinal (coherent) illumination was accomplished using an imaging interface comprised of a short-focal length imaging lens and a contact lens. The magnification between the camera and retina (spatial sampling) was appropriately chosen to record the microscopic structural features of the retina in the image. A pupil stop was employed in the detection path to reject unwanted backscattering from the mouse eye and other sources and limit aberrations distorting the retinal images. In vivo mouse retinal imaging was performed at a sweep rate of 150 Hz to acquire volumes unaffected by the system vibrations, which predominated at lower frequencies. Operating the FF-SS-OCT at this speed yielded an effective axial scan rate of 20 million A-scans/s and a field of view of 820 × 410 µm (24.12° × 12.06°). High-quality retinal B-scans and enface images of the retina were obtained with the SS-FF-OCT, revealing all major retinal layers and vascular plexuses.
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