Evidence map›Paper›PMID 39145903›Full record

ReviewCurrent allergy and asthma reports2024

Childhood-Onset Systemic Lupus Erythematosus (cSLE): An International Perspective.

Amita Aggarwal, Taciana A P Fernandes, Angela Migowa, Eve M D Smith, Maria Hanif, Kate Webb, Laura B Lewandowski

Abstract readReview
In one paragraph

Review in Current allergy and asthma reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Amita AggarwalDepartment of Clinical Immunology & Rheumatology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.ORCID http://orcid.org/0000-0002-2187-5186
Taciana A P FernandesDepartment of Pediatrics, Medical School, São Paulo State University (UNESP), Botucatu, Sao Paulo, Brazil.ORCID http://orcid.org/0000-0001-7681-8915
Angela MigowaDepartment of Paediatrics and Child Health, Aga Khan University, 3Rd Parklands Avenue, P.O.BOX 30270 00100 GPO, Nairobi, Kenya.ORCID http://orcid.org/0000-0002-1146-7963
Eve M D SmithDepartment of Women's & Children's Health, Institute of Life Course and Medical Sciences, Faculty of Health and Life Sciences, University of Liverpool, Liverpool, UK.
Maria HanifDepartment of Women's & Children's Health, Institute of Life Course and Medical Sciences, Faculty of Health and Life Sciences, University of Liverpool, Liverpool, UK.ORCID http://orcid.org/0000-0002-8371-7597
Kate WebbRed Cross War Memorial Children's Hospital, University of Cape Town, Cape Town, South Africa.ORCID http://orcid.org/0000-0003-1087-5946
Laura B LewandowskiLupus Genomics and Global Health Disparities Unit, Systemic Autoimmunity Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, USA. laura.lewandowski@nih.gov.ORCID http://orcid.org/0000-0002-4253-2545

Funding

Genetics and pathophysiology of systemic lupus erythematosus in global populationsZIAAR041214 · NIAMS · NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES · PI LEWANDOWSKI, LAURA · 2021 to 2025
$4.5M
6 · The paper itself

Abstract

purpose of reviewChildhood-onset systemic lupus erythematosus (cSLE) is a severe and potentially life-threatening chronic autoimmune disease. cSLE is more aggressive and has poorer outcomes than adult-onset disease. The global burden of cSLE is poorly understood, with most publications on cSLE originating from high-resourced settings. The reports from less resourced settings indicate high morbidity and mortality in these populations. RECENT

findingsIn this article, we review the disparities in global access to rheumatology care and research for patients with cSLE. We highlight recent cSLE advances from all regions of the globe. We describe current obstacles to cSLE clinical care and research in all settings. Finally, we propose a path forward for high quality, equitable and accessible care to individuals with cSLE everywhere. Individuals with cSLE are at risk for morbidity and death, yet patients worldwide face challenges to adequate access to care and research. Sustained, collaborative efforts are needed to create pathways to improve care and outcomes for these patients.

Indexed as

Age of OnsetLupus Erythematosus, SystemicChildGlobal HealthHealth Services AccessibilityHumansChildhood-onset lupusGlobal healthLupusPediatricPediatric rheumatology

Identifiers

PMID39145903
PMCPMC11377481

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.