Evidence map›Paper›PMID 39145656›Full record

ArticlemBio2024

Natural selection and recombination at host-interacting lipoprotein loci drive genome diversification of Lyme disease and related bacteria.

Saymon Akther, Emmanuel F Mongodin, Richard D Morgan, Lia Di, Xiaohua Yang, Maryna Golovchenko, Natalie Rudenko, Gabriele Margos, Sabrina Hepner, Volker Fingerle and 10 more

Abstract read
In one paragraph

Article in mBio, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Lyme borreliosis.Nature reviews. Disease primers · 2026
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Saymon AktherGraduate Center and Hunter College, City University of New York, New York, New York, USA.ORCID 0000-0002-9084-9379
Emmanuel F MongodinUniversity of Maryland School of Medicine, Baltimore, Maryland, USA.
Richard D MorganNew England BioLabs, Ipswich, Massachusetts, USA.
Lia DiGraduate Center and Hunter College, City University of New York, New York, New York, USA.ORCID 0000-0003-1957-6475
Xiaohua YangDepartment of Medicine, Renaissance School of Medicine, Stony Brook University (SUNY), Stony Brook, New York, USA.
Maryna GolovchenkoBiology Centre Czech Academy of Sciences, Institute of Parasitology, České Budějovice, Czech Republic.
Natalie RudenkoBiology Centre Czech Academy of Sciences, Institute of Parasitology, České Budějovice, Czech Republic.
Gabriele MargosBavarian Health and Food Safety Authority and German National Reference Centre for Borrelia, Oberschleissheim, Bavaria, Germany.
Sabrina HepnerBavarian Health and Food Safety Authority and German National Reference Centre for Borrelia, Oberschleissheim, Bavaria, Germany.
Volker FingerleBavarian Health and Food Safety Authority and German National Reference Centre for Borrelia, Oberschleissheim, Bavaria, Germany.
Hiroki KawabataNational Institute of Infectious Diseases, Tokyo, Japan.
Ana Cláudia NorteDepartment of Life Sciences, University of Coimbra, MARE-Marine and Environmental Sciences Centre, Coimbra, Portugal.
Isabel Lopes de CarvalhoCentre for Vector and Infectious Diseases Research, Águas de Moura, Portugal.
Maria Sofia NúncioCentre for Vector and Infectious Diseases Research, Águas de Moura, Portugal.
Adriana MarquesNational Institute of Allergy and Infectious Diseases, Bethesda, Maryland, USA.ORCID 0000-0002-5403-4551
Steven E SchutzerNew Jersey Medical School, Newark, New Jersey, USA.
Claire M FraserUniversity of Maryland School of Medicine, Baltimore, Maryland, USA.
Benjamin J LuftDepartment of Medicine, Renaissance School of Medicine, Stony Brook University (SUNY), Stony Brook, New York, USA.ORCID 0000-0001-9008-7004
Sherwood R CasjensUniversity of Utah School of Medicine and School of Biological Sciences, Salt Lake City, Utah, USA.ORCID 0000-0002-1213-7130
Weigang QiuGraduate Center and Hunter College, City University of New York, New York, New York, USA.ORCID 0000-0003-4585-1872

Funding

Technology CoreU19AI110820 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI FRASER, CLAIRE M., RASKO, DAVID A · 2014 to 2023
$36.5M
ImmunoPET Probes for the Imaging of Lyme DiseaseR01AI175417 · NIAID · HUNTER COLLEGE · PI Maria Gomes-Solecki, WEIGANG QIU · 2023 to 2026
$2.2M
Genomic & Host Drivers of Borrelia DiversificationR21AI139782 · NIAID · HUNTER COLLEGE · PI QIU, WEIGANG · 2018 to 2019
$429k
HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) R01AI175417HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) R21AI139782HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) U19AI110820HHS | NIH | NIAID | Division of Intramural Research (DIR, NIAID)NIAID NIH HHS R01 AI175417NIAID NIH HHS R21 AI139782NIAID NIH HHS U19 AI110820Steven and Alexandra Cohen Foundation (Steven & Alexandra Cohen Foundation)
6 · The paper itself

Abstract

Lyme disease, caused by spirochetes in the IMPORTANCE: Lyme disease (also called Lyme borreliosis in Europe), a condition caused by spirochete bacteria of the genus

Indexed as

Genome, BacterialLipoproteinsLyme DiseasePhylogenyRecombination, GeneticSelection, GeneticAnimalsBorreliaBorrelia burgdorferiBorrelia burgdorferi GroupEuropeEvolution, MolecularGenetic VariationHost Microbial InteractionsHumansIxodesLipoproteinsBorrelia burgdorferievolutiongenome diversificationLyme diseaseplasmidsrecombination

Identifiers

PMID39145656
PMCPMC11389397

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.