Evidence map›Paper›PMID 39145535›Full record

ArticleInfluenza and other respiratory viruses2024

Early COVID-19 XBB.1.5 Vaccine Effectiveness Against Hospitalisation Among Adults Targeted for Vaccination, VEBIS Hospital Network, Europe, October 2023-January 2024.

Liliana Antunes, Clara Mazagatos, Iván Martínez-Baz, Reinout Naesens, Maria-Louise Borg, Goranka Petrović, Terra Fatukasi, Ligita Jancoriene, Ausenda Machado, Beatrix Oroszi and 20 more

Abstract readMulticenter Study
In one paragraph

Article in Influenza and other respiratory viruses, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

30 authors.

Liliana AntunesEpidemiology Department, Epiconcept, Paris, France.ORCID 0000-0003-0453-5304
Clara MazagatosNational Centre for Epidemiology, Institute of Health Carlos III, Madrid, Spain.ORCID 0000-0002-6909-6923
Iván Martínez-BazConsortium for Biomedical Research in Epidemiology and Public Health (CIBERESP), Madrid, Spain.ORCID 0000-0002-3405-2277
Reinout NaesensDepartment of Medical Microbiology and Infection Prevention & Control, Ziekenhuisnetwerk Antwerpen, Antwerp, Belgium.ORCID 0000-0003-1004-7737
Maria-Louise BorgInfectious Disease Prevention and Control Unit (IDCU), Health Promotion and Disease Prevention, Msida, Malta.
Goranka PetrovićCroatian Institute of Public Health, Zagreb, Croatia.ORCID 0000-0001-8304-5519
Terra FatukasiHealth Service Executive-Health Protection Surveillance Centre (HPSC), Dublin, Ireland.ORCID 0000-0003-3287-1831
Ligita JancorieneClinic of Infectious Diseases and Dermatovenerology, Institute of Clinical Medicine, Medical Faculty, Vilnius University, Vilnius, Lithuania.ORCID 0000-0001-6488-6312
Ausenda MachadoEpidemiology Department, National Health Institute Doutor Ricardo Jorge, Lisbon, Portugal.ORCID 0000-0002-1849-1499
Beatrix OrosziNational Laboratory for Health Security, Epidemiology and Surveillance Centre, Semmelweis University, Budapest, Hungary.ORCID 0000-0001-8915-0336
Petr HusaUniversity Hospital Brno, Masaryk University, Brno, Czechia.ORCID 0000-0002-9190-2610
Mihaela LazarCantacuzino National Military-Medical Institute for Research and Development, Bucharest, Romania.ORCID 0000-0002-8226-6026
Ralf DürrwaldNational Reference Centre for Influenza, Robert Koch Institute, Berlin, Germany.ORCID 0000-0002-3432-0438
Jennifer HowardEpidemiology Department, Epiconcept, Paris, France.ORCID 0009-0008-1930-8693
Aryse MeloInfectious Diseases Department, National Health Institute Doutor Ricardo Jorge, Lisbon, Portugal.ORCID 0000-0002-6655-8715
Gloria Pérez-GimenoNational Centre for Epidemiology, Institute of Health Carlos III, Madrid, Spain.ORCID 0000-0003-3435-4854
Jesús CastillaConsortium for Biomedical Research in Epidemiology and Public Health (CIBERESP), Madrid, Spain.ORCID 0000-0002-6396-7265
Eva BernaertDepartment of Medical Microbiology and Infection Prevention & Control, Ziekenhuisnetwerk Antwerpen, Antwerp, Belgium.
Aušra DžiugytėInfectious Disease Prevention and Control Unit (IDCU), Health Promotion and Disease Prevention, Msida, Malta.ORCID 0000-0003-0486-8491
Zvjezdana Lovrić MakarićCroatian Institute of Public Health, Zagreb, Croatia.ORCID 0000-0003-4285-2116
Margaret FitzgeraldHealth Service Executive-Health Protection Surveillance Centre (HPSC), Dublin, Ireland.ORCID 0000-0002-4535-0966
Auksė MickienėDepartment of Infectious Diseases, Lithuanian University of Health Sciences, Kaunas, Lithuania.
Verónica GomezEpidemiology Department, National Health Institute Doutor Ricardo Jorge, Lisbon, Portugal.ORCID 0000-0003-0485-0005
Gergő TúriNational Laboratory for Health Security, Epidemiology and Surveillance Centre, Semmelweis University, Budapest, Hungary.ORCID 0000-0003-3465-8321
Lenka SoučkováUniversity Hospital Brno, Masaryk University, Brno, Czechia.ORCID 0000-0003-0028-4464
Alexandru MarinDr Victor Babes Clinical Hospital of Infectious and Tropical Diseases, Bucharest, Romania.ORCID 0009-0000-7668-9607
Kristin TolksdorfDepartment for Infectious Disease Epidemiology, Robert Koch Institute, Berlin, Germany.ORCID 0000-0002-8712-6399
Nathalie NicolayEuropean Centre for Disease Prevention and Control, Stockholm, Sweden.ORCID 0000-0002-5916-7855
Angela M C RoseEpidemiology Department, Epiconcept, Paris, France.ORCID 0000-0002-2493-8082
European Hospital Vaccine Effectiveness Group

Funding

European Centre for Disease Prevention and Control ECDC/2021/016
6 · The paper itself

Abstract

We conducted a multicentre test-negative case-control study covering the period from October 2023 to January 2024 among adult patients aged ≥ 18 years hospitalised with severe acute respiratory infection in Europe. We provide early estimates of the effectiveness of the newly adapted XBB.1.5 COVID-19 vaccines against PCR-confirmed SARS-CoV-2 hospitalisation. Vaccine effectiveness was 49% overall, ranging between 69% at 14-29 days and 40% at 60-105 days post vaccination. The adapted XBB.1.5 COVID-19 vaccines conferred protection against COVID-19 hospitalisation in the first 3.5 months post vaccination, with VE > 70% in older adults (≥ 65 years) up to 1 month post vaccination.

Indexed as

COVID-19COVID-19 VaccinesHospitalizationSARS-CoV-2VaccinationVaccine EfficacyAdolescentAdultAgedAged, 80 and overCase-Control StudiesEuropeFemaleHumansMaleMiddle AgedCOVID-19 VaccinesCOVID‐19 XBB.1.5 vaccineEuropeSARS‐CoV‐2 hospitalisationvaccine effectiveness

Identifiers

PMID39145535
PMCPMC11325250

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.