Evidence map›Paper›PMID 39145534›Full record

ArticleOncotarget2024

A nanobody against the V-ATPase c subunit inhibits metastasis of 4T1-12B breast tumor cells to lung in mice.

Zhen Li, Mohammed A Alshagawi, Rebecca A Oot, Mariam K Alamoudi, Kevin Su, Wenhui Li, Michael P Collins, Stephan Wilkens, Michael Forgac

Abstract read
In one paragraph

Article in Oncotarget, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Zhen Li *Program in Pharmacology and Drug Development, Graduate School of Biomedical Sciences, Tufts University, Boston, MA 02111, USA.
Mohammed A Alshagawi *Program in Pharmacology and Drug Development, Graduate School of Biomedical Sciences, Tufts University, Boston, MA 02111, USA.
Rebecca A OotDepartment of Biochemistry and Molecular Biology, SUNY Upstate Medical University, Syracuse, NY 13210, USA.
Mariam K AlamoudiDepartment of Developmental, Molecular, and Chemical Biology, Tufts University School of Medicine, Boston, MA 02111, USA.
Kevin SuProgram in Pharmacology and Drug Development, Graduate School of Biomedical Sciences, Tufts University, Boston, MA 02111, USA.
Wenhui LiProgram in Pharmacology and Drug Development, Graduate School of Biomedical Sciences, Tufts University, Boston, MA 02111, USA.
Michael P CollinsProgram in Cellular, Molecular and Developmental Biology, Graduate School of Biomedical Sciences, Tufts University, Boston, MA 02111, USA.
Stephan WilkensDepartment of Biochemistry and Molecular Biology, SUNY Upstate Medical University, Syracuse, NY 13210, USA.
Michael ForgacDepartment of Developmental, Molecular, and Chemical Biology, Tufts University School of Medicine, Boston, MA 02111, USA.

Funding

Structure and Regulatory Mechanisms of the Vacuolar ATPaseR35GM141908 · NIGMS · UPSTATE MEDICAL UNIVERSITY · PI WILKENS, STEPHAN · 2021 to 2025
$2.1M
Function of V-ATPases in Breast Cancer MetastasisR21CA245172 · NCI · TUFTS UNIVERSITY BOSTON · PI FORGAC, MICHAEL D, KUPERWASSER, CHARLOTTE · 2021 to 2022
$413k
NCI NIH HHS R21 CA245172NIGMS NIH HHS R35 GM141908
6 · The paper itself

Abstract

The vacuolar H

Indexed as

Lung NeoplasmsSingle-Domain AntibodiesVacuolar Proton-Translocating ATPasesAnimalsBreast NeoplasmsCell Line, TumorFemaleHumansMiceMice, Inbred BALB CNeoplasm InvasivenessSingle-Domain AntibodiesVacuolar Proton-Translocating ATPasesbreast cancerinvasiontumor growthtumor metastasisvacuolar ATPase

Identifiers

PMID39145534
PMCPMC11325586

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.