Evidence map›Paper›PMID 39145459›Full record

ArticleThe Journal of clinical investigation2024

Improving radiotherapy in immunosuppressive microenvironments by targeting complement receptor C5aR1.

Callum Beach, David MacLean, Dominika Majorova, Stavros Melemenidis, Dhanya K Nambiar, Ryan K Kim, Gabriel N Valbuena, Silvia Guglietta, Carsten Krieg, Mahnaz Darvish-Damavandi and 24 more

Abstract readPublished Erratum
In one paragraph

Article in The Journal of clinical investigation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. The complement system in intestinal inflammation and cancer.The Journal of clinical investigation · 2025
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

34 authors.

Callum Beach
David MacLean
Dominika Majorova
Stavros Melemenidis
Dhanya K Nambiar
Ryan K Kim
Gabriel N Valbuena
Silvia Guglietta
Carsten Krieg
Mahnaz Darvish-Damavandi
Tatsuya Suwa
Alistair Easton
Lily Vs Hillson
Ashley K McCulloch
Ross K McMahon
Kathryn Pennel
Joanne Edwards
Sean M O'Cathail
Campbell S Roxburgh
Enric Domingo
Eui Jung Moon
Dadi Jiang
Yanyan Jiang
Qingyang Zhang
Albert C Koong
Trent M Woodruff
Edward E Graves
Tim Maughan
Simon Ja Buczacki
Manuel Stucki
Quynh-Thu Le
Simon J Leedham
Amato J Giaccia
Monica M Olcina

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Receptor, Anaphylatoxin C5aAnimalsHumansMiceNeoplasmsTumor MicroenvironmentC5AR1 protein, humanReceptor, Anaphylatoxin C5a

Identifiers

PMID39145459
PMCPMC11324292

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.