Evidence map›Paper›PMID 39145102›Full record

ArticleNIHR open research2024

Baseline Characteristics in the Remote Diet Intervention to REduce long-COVID Symptoms Trial (ReDIRECT).

Laura Haag, Janice Richardson, Caroline Haig, Yvonne Cunningham, Heather Fraser, Naomi Brosnahan, Tracy Ibbotson, Jane Ormerod, Chris White, Emma McIntosh and 6 more

Abstract read
In one paragraph

Article in NIHR open research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Laura HaagHuman Nutrition, School of Medicine, Dentistry & Nursing, University of Glasgow, Glasgow, Scotland, G31 2ER, UK.ORCID https://orcid.org/0000-0003-3342-1365
Janice RichardsonSchool of Cardiovascular and Metabolic Health, University of Glasgow, Glasgow, Scotland, G12 8TA, UK.ORCID https://orcid.org/0000-0002-8207-0891
Caroline HaigRobertson Centre for Biostatistics, School of Health and Wellbeing, University of Glasgow, Glasgow, Scotland, G12 8TA, UK.
Yvonne CunninghamGeneral Practice & Primary Care, School of Health and Wellbeing, University of Glasgow, Glasgow, Scotland, G12 8TA, UK.ORCID https://orcid.org/0000-0002-7533-8933
Heather FraserHealth Economics and Health Technology Assessment, School of Health and Wellbeing, University of Glasgow, Glasgow, Scotland, G12 8TA, UK.
Naomi BrosnahanCounterweight Ltd., Abergavenny, UK.
Tracy IbbotsonGeneral Practice & Primary Care, School of Health and Wellbeing, University of Glasgow, Glasgow, Scotland, G12 8TA, UK.ORCID https://orcid.org/0000-0002-9224-6467
Jane OrmerodLong Covid Scotland, UK, UK.
Chris WhiteLong Covid Scotland, UK, UK.
Emma McIntoshHealth Economics and Health Technology Assessment, School of Health and Wellbeing, University of Glasgow, Glasgow, Scotland, G12 8TA, UK.ORCID https://orcid.org/0000-0001-6340-3083
Kate O'DonnellGeneral Practice & Primary Care, School of Health and Wellbeing, University of Glasgow, Glasgow, Scotland, G12 8TA, UK.
Naveed SattarSchool of Cardiovascular and Metabolic Health, University of Glasgow, Glasgow, Scotland, G12 8TA, UK.
Alex McConnachieRobertson Centre for Biostatistics, School of Health and Wellbeing, University of Glasgow, Glasgow, Scotland, G12 8TA, UK.ORCID https://orcid.org/0000-0002-7262-7000
Mike LeanHuman Nutrition, School of Medicine, Dentistry & Nursing, University of Glasgow, Glasgow, Scotland, G31 2ER, UK.
David BlaneGeneral Practice & Primary Care, School of Health and Wellbeing, University of Glasgow, Glasgow, Scotland, G12 8TA, UK.ORCID https://orcid.org/0000-0002-3872-3621
Emilie CombetHuman Nutrition, School of Medicine, Dentistry & Nursing, University of Glasgow, Glasgow, Scotland, G31 2ER, UK.ORCID https://orcid.org/0000-0002-9302-8971

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The persistence of symptoms for ≥12 weeks after a COVID-19 infection is known as Long COVID (LC), a condition with unclear pathophysiology and no proven treatments to date. Living with obesity is a risk factor for LC and has symptoms which may overlap with and aggravate LC. Methods: ReDIRECT is a remotely delivered trial assessing whether weight management can reduce LC symptoms. We recruited people with LC and BMI >27kg/m Results: Participants (n=234) in England (64%) and Scotland (30%) were mainly women (85%) of white ethnicity (90%), with 13% living in the 20% most deprived areas, a mean age of 46 (SD10) years, and median BMI of 35kg/m Conclusions: Symptoms linked to LC and overweight are diverse and complex. Remote trial delivery enabled rapid recruitment across the UK yet certain groups (e.g. men and those from ethnic minority groups) were under-represented. Trial registration: ISRCTN registry ( ISRCTN12595520, 25/11/2021).

Indexed as

BreathlessnessDietFatigueLong COVIDPainPersonalisationPost COVID-19 SyndromeRemote deliveryWeight management

Identifiers

PMID39145102
PMCPMC11320183

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.