Evidence map›Paper›PMID 39145015›Full record

ReviewHeliyon2024

Effect of genetic profiling on surgical decisions at hereditary colorectal cancer syndromes.

Yasaman Goudarzi, Khaterehsadat Monirvaghefi, Salar Aghaei, Seyed Siamak Amiri, Mahdi Rezaei, Atefeh Dehghanitafti, Ali Azarpey, Alireza Azani, SeyedAbbas Pakmehr, Hamid Reza Eftekhari and 3 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Heliyon, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Review
  6. Review
  7. Therapeutic Significance of NLRP3 Inflammasome in Cancer: Friend or Foe?International journal of molecular sciences · 2024
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Yasaman GoudarziDepartment of Medical Science, Shahroud Branch, Islamic Azad University, Iran.
Khaterehsadat MonirvaghefiDepartment of Adult Hematology & Oncology, School of Medicine, Ayatollah Khansari Hospital, Arak University of Medical Sciences, Arak, Iran.
Salar AghaeiFaculty of Medicine, Medical University of Kurdistan, Sanandaj, Iran.
Seyed Siamak AmiriDepartment of Medicine, Tehran University of Medical Sciences (TUMS), Tehran, Iran.
Mahdi RezaeiClinical Research Department, Pasteur Institute of Iran, Tehran, Iran.
Atefeh DehghanitaftiDepartment of General Surgery, School of Medicine, Golestan University of Medical Sciences, Gorgan, Iran.
Ali AzarpeyEmory University School of Medicine, Atlanta, GA, USA.
Alireza AzaniDepartment of Medical Genetics, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
SeyedAbbas PakmehrSchool of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Hamid Reza EftekhariDrug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Safa TahmasebiStudent Research Committee, Department of Immunology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Shahriar Zohourian ShahzadiErfan Hospital, Iran University of Medical Sciences, Tehran, Iran.
Mansour RajabivahidDepartment of Internal Medicine, Valiasr Hospital, Zanjan University of Medical Sciences, Zanjan, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hereditary colorectal cancer syndromes, such as Lynch syndrome and familial adenomatous polyposis (FAP), present significant clinical challenges due to the heightened cancer risks associated with these genetic conditions. This review explores genetic profiling impact on surgical decisions for hereditary colorectal cancer (HCRC), assessing options, timing, and outcomes. Genotypes of different HCRCs are discussed, revealing a connection between genetic profiles, disease severity, and outcomes. For Lynch syndrome, mutations in the

Indexed as

Colorectal cancerFamilial adenomatous polyposisHereditary non-polyposis colorectal cancerLynch syndrome

Identifiers

PMID39145015
PMCPMC11320152

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.