Evidence map›Paper›PMID 39144923›Full record

ReviewHeliyon2024

Polysaccharide hydrogels for skin wound healing.

Meifen Liu, Jiman Jin, Xiqiang Zhong, Liangle Liu, Chengxuan Tang, Limei Cai

Abstract readReview
In one paragraph

Review in Heliyon, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Biomimetic materials for medical applications.Chinese medical journal · 2026
    Review
  5. Review
  6. Review
  7. Article
  8. Polysaccharide based biomaterials for advanced wound healing applications.Frontiers in cellular and infection microbiology · 2026
    Review
  9. Review
  10. Review
  11. Review
  12. Smart Hydrogels in Wearable Electronics for Wound Treatments.Small (Weinheim an der Bergstrasse, Germany) · 2025
    Review
  13. Article
  14. Healing Efficacy ofGels (Basel, Switzerland) · 2025
    Article
  15. Poloxamer-based hydrogel with EGCG and rhEGF for diabetic foot ulcer treatment.Journal of materials science. Materials in medicine · 2025
    Article
  16. Article
  17. Review
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Meifen LiuThe Third Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325200, China.
Jiman JinThe Third Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325200, China.
Xiqiang ZhongThe Third Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325200, China.
Liangle LiuThe Third Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325200, China.
Chengxuan TangThe Third Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325200, China.
Limei CaiThe Third Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325200, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Advances in the development and utilization of polysaccharide materials are highly promising, offering prominent applications in the field of tissue engineering for addressing diverse clinical needs, including wound healing, bone regeneration, cartilage repair, and treatment of conditions such as arthritis. Novel polysaccharide materials are popular owing to their inherent stability, biocompatibility, and repeatability. This review presents an overview of the biomedical applications of natural polysaccharide hydrogels and their derivatives. Herein, we discuss the latest advancements in the fabrication, physicochemical properties, and biomedical applications of polysaccharide-based hydrogels, including chitosan, hyaluronic acid, alginate, and cellulose. Various processing techniques applicable to polysaccharide materials are explored, such as the transformation of polysaccharide hydrogels into electrospun nanofibers, microneedles, microspheres, and nanogels. Furthermore, the use of polysaccharide hydrogels in the context of wound-healing applications, including hemostatic effects, antimicrobial activities, anti-inflammatory properties, and promotion of angiogenesis, is presented. Finally, we address the challenges encountered in the development of polysaccharide hydrogels and outline the potential prospects in this evolving field.

Indexed as

HydrogelPolysaccharideRegenerative medicineSkin woundTissue repairing

Identifiers

PMID39144923
PMCPMC11320479

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.