Evidence map›Paper›PMID 39144922›Full record

ReviewHeliyon2024

Targeted therapy for leukemia based on nanomaterials.

Suying Qian, Cuiping Zheng, Yanfang Wu, Huiyan Huang, Gongqiang Wu, Junyu Zhang

Abstract readReview
In one paragraph

Review in Heliyon, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Suying QianDepartment of Hematology and Oncology, Ningbo No.2 Hospital, Ningbo, 315000, China.
Cuiping ZhengDepartment of Hematology and Oncology, Wenzhou Central Hospital, Wenzhou, 325099, China.
Yanfang WuDepartment of Hematopathology, The First People's Hospital of Fuyang, Hangzhou, 311499, China.
Huiyan HuangDepartment of Hematopathology, The First People's Hospital of Fuyang, Hangzhou, 311499, China.
Gongqiang WuDepartment of Hematology and Oncology, Dongyang People's Hospital, Jinhua, 322103, China.
Junyu ZhangDepartment of Hematopathology, Lishui Central Hospital, Lishui, 323020, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Leukemia is a kind of hematopoietic stem cell malignant clonal disease. Drug therapy is the core treatment strategy for leukemia, but the current therapeutic drugs have defects such as low bioavailability, large adverse reactions and inconvenient intravenous administration. Targeted therapy can combine drugs with specific carcinogenic sites on cells to kill cancer cells and avoid damage to normal cells, which has gradually become the mainstream method of leukemia treatment. In addition, nanomedicine delivery systems can significantly improve drug efficacy through controlled size and targeted optimization of drug delivery by modification strategies. Therefore, the targeted treatment of leukemia based on nanomaterials has great research value and application prospect. This paper gives an overview of the current therapeutic strategies for leukemia, and then reviews the cutting-edge targeted therapeutic nanomaterials for leukemia, including organic nanomaterials (mainly carbon-based nanomaterials, lipid materials, polymers, etc.) and inorganic nanomaterials (mainly noble metal nanoparticles, magnetic nanoparticles, hollow mesoporous materials, etc.). The challenges and prospects for the future development of targeted nanomaterials in the treatment of leukemia are also briefly reviewed.

Indexed as

LeukemiaNanomaterialsTargeted therapy

Identifiers

PMID39144922
PMCPMC11320317

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.