ArticleSchizophrenia bulletin open2022
Dysmaturational Longitudinal Epigenetic Aging During Transition to Psychosis.
Article in Schizophrenia bulletin open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed.
- The association between epigenetic ageing from childhood to early adulthood and psychotic-like experiences in early adulthood.Psychological medicine · 2025Article
- Article
- Epigenetic age across development in children and adolescents with ADHD.Psychiatry research · 2025Article
- Maximizing insights from longitudinal epigenetic age data: simulations, applications, and practical guidance.Clinical epigenetics · 2024Article
- Immunophenotypes in psychosis: is it a premature inflamm-aging disorder?Molecular psychiatry · 2024Review
- Maximizing Insights from Longitudinal Epigenetic Age Data: Simulations, Applications, and Practical Guidance.Research square · 2024Article
- Accelerated Pace of Aging in Schizophrenia: Five Case-Control Studies.Biological psychiatry · 2024Article
- The Cutting Edge of Epigenetic Clocks: In Search of Mechanisms Linking Aging and Mental Health.Biological psychiatry · 2023Review
- Epigenetic age deacceleration in youth at familial risk for schizophrenia and bipolar disorder.Translational psychiatry · 2023Article
- Subjective Overview of Accelerated Aging in Schizophrenia.International journal of environmental research and public health · 2022Review
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Psychosis frequently occurs during adolescence and young adulthood, possibly as a result of gene-environment interactions, mediated by epigenetic mechanisms such as DNA methylation. Methylation patterns can be leveraged to predict epigenetic age in order to identify anomalies in aging trajectories that may be associated with the emergence of psychosis. Thus, epigenetic age may provide a measurable surrogate of psychotic risk or psychosis' emergence, and shed light on the neurodevelopmental model of psychosis. In this study, we present the first longitudinal analysis of epigenetic age trajectory during conversion to psychosis in a population at ultra-high-risk, with available genome-wide methylation DNA at two time points, at baseline and after one year of follow-up (
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