Evidence map›Paper›PMID 39144760›Full record

ArticleSchizophrenia bulletin open2022

The Electroretinogram as a Potential Biomarker of Psychosis in Children at Familial Risk.

Isabel Moreau, Marc Hébert, Michel Maziade, Alexandra Painchaud, Chantal Mérette

Abstract read
In one paragraph

Article in Schizophrenia bulletin open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. The origins of the full-field flash electroretinogram b-wave.Frontiers in molecular neuroscience · 2023
    Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Isabel MoreauCentre de recherche CERVO, Centre intégré de santé et de services sociaux de la Capitale-Nationale, Québec, QC, Canada.ORCID https://orcid.org/0000-0002-9748-7307
Marc HébertCentre de recherche CERVO, Centre intégré de santé et de services sociaux de la Capitale-Nationale, Québec, QC, Canada.
Michel MaziadeCentre de recherche CERVO, Centre intégré de santé et de services sociaux de la Capitale-Nationale, Québec, QC, Canada.
Alexandra PainchaudCentre de recherche CERVO, Centre intégré de santé et de services sociaux de la Capitale-Nationale, Québec, QC, Canada.
Chantal MéretteCentre de recherche CERVO, Centre intégré de santé et de services sociaux de la Capitale-Nationale, Québec, QC, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We previously proposed the electroretinogram (ERG) as a promising biomarker of major psychiatric disorders such as schizophrenia (SZ) and bipolar disorder (BP), given that we found anomalies in the ERG parameters of patients with these diagnoses as well as in their children who are at high risk (HR) of developing such disorders. The aim of the present study is to investigate the usefulness of the ERG for individual detection, among HR children, of an ERG profile resembling that of a SZ patient, as this may indicate a stronger likelihood of transition to psychosis. Using a logistic regression model previously derived from the ERG assessments of SZ patients and control (CT) subjects, individual risk scores were obtained for 61 HR and 80 CT youth. Those with a very high individual risk score were classified as "schizophrenia-like" (

Indexed as

bipolar disorderfamilial high riskindividualized riskpredictionschizophreniavalidation

Identifiers

PMID39144760
PMCPMC11206048

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.