Evidence map›Paper›PMID 39144408›Full record

ReviewDEN open2025

Endoscopic detection and diagnosis of gastric cancer using image-enhanced endoscopy: A systematic review and meta-analysis.

Osamu Dohi, Mayuko Seya, Naoto Iwai, Tomoko Ochiai, Junki Yumoto, Hiroki Mukai, Katsuma Yamauchi, Reo Kobayashi, Ryohei Hirose, Ken Inoue and 3 more

Abstract readReview
In one paragraph

Review in DEN open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Clinical Performance of Gastric CADe: Beyond Lesion Recognition From the G-CADe Trial.Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society · 2026
    Article
  3. Prevention of Gastric Cancer.Medicina (Kaunas, Lithuania) · 2026
    Review
  4. Article
  5. ATR-CHK1 Axis Inhibitors in Gastric Cancer Treatment.International journal of molecular sciences · 2025
    Review
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Osamu DohiMolecular Gastroenterology and Hepatology Graduate School of Medicine, Kyoto Prefectural University of Medicine Kyoto Japan.ORCID https://orcid.org/0000-0002-0498-0144
Mayuko SeyaMolecular Gastroenterology and Hepatology Graduate School of Medicine, Kyoto Prefectural University of Medicine Kyoto Japan.
Naoto IwaiMolecular Gastroenterology and Hepatology Graduate School of Medicine, Kyoto Prefectural University of Medicine Kyoto Japan.
Tomoko OchiaiMolecular Gastroenterology and Hepatology Graduate School of Medicine, Kyoto Prefectural University of Medicine Kyoto Japan.
Junki YumotoMolecular Gastroenterology and Hepatology Graduate School of Medicine, Kyoto Prefectural University of Medicine Kyoto Japan.
Hiroki MukaiMolecular Gastroenterology and Hepatology Graduate School of Medicine, Kyoto Prefectural University of Medicine Kyoto Japan.
Katsuma YamauchiMolecular Gastroenterology and Hepatology Graduate School of Medicine, Kyoto Prefectural University of Medicine Kyoto Japan.
Reo KobayashiMolecular Gastroenterology and Hepatology Graduate School of Medicine, Kyoto Prefectural University of Medicine Kyoto Japan.
Ryohei HiroseMolecular Gastroenterology and Hepatology Graduate School of Medicine, Kyoto Prefectural University of Medicine Kyoto Japan.
Ken InoueMolecular Gastroenterology and Hepatology Graduate School of Medicine, Kyoto Prefectural University of Medicine Kyoto Japan.
Naohisa YoshidaMolecular Gastroenterology and Hepatology Graduate School of Medicine, Kyoto Prefectural University of Medicine Kyoto Japan.ORCID https://orcid.org/0000-0001-6167-9705
Hideyuki KonishiMolecular Gastroenterology and Hepatology Graduate School of Medicine, Kyoto Prefectural University of Medicine Kyoto Japan.
Yoshito ItohMolecular Gastroenterology and Hepatology Graduate School of Medicine, Kyoto Prefectural University of Medicine Kyoto Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: We aimed to conduct a systematic review and meta-analysis to assess the value of image-enhanced endoscopy including blue laser imaging (BLI), linked color imaging, narrow-band imaging (NBI), and texture and color enhancement imaging to detect and diagnose gastric cancer (GC) compared to that of white-light imaging (WLI). Methods: Studies meeting the inclusion criteria were identified through PubMed, Cochrane Library, and Japan Medical Abstracts Society databases searches. The pooled risk ratio for dichotomous variables was calculated using the random-effects model to assess the GC detection between WLI and image-enhanced endoscopy. A random-effects model was used to calculate the overall diagnostic performance of WLI and magnifying image-enhanced endoscopy for GC. Results: Sixteen studies met the inclusion criteria. The detection rate of GC was significantly improved in linked color imaging compared with that in WLI (risk ratio, 2.20; 95% confidence interval [CI], 1.39-3.25; Conclusions: Our meta-analysis showed a high detection rate for linked color imaging and a high diagnostic performance of ME-NBI/BLI for GC compared to that with WLI.

Indexed as

blue laser imaginggastric cancerimage‐enhanced endoscopylinked color imagingnarrow‐band imaging

Identifiers

PMID39144408
PMCPMC11322228

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.