ArticleJournal of thoracic disease2024
Prevalence and management of pulmonary nodules: a systematic review and meta-analysis.
Article in Journal of thoracic disease, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
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Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Systematic review and single-arm meta-analysis of the clinical value of multidisciplinary team-based multimodal interventions in pulmonary nodule management.Frontiers in oncology · 2026Pooled it
- Risk factors for the growth of ground-glass nodules in the lungs: A systematic review and meta-analysis.Clinics (Sao Paulo, Brazil) · 2025Pooled it
- A transfer learning-based hybrid deep- and machine-learning regression approach for predicting the postoperative pulmonary function.European radiology experimental · 2026Article
- Micro-CT dynamic changes and molecular mechanisms in a pulmonary nodule mouse model induced by Benzo[a]pyrene and lipopolysaccharide.Journal of thoracic disease · 2026Article
- Clinicopathological discordance and survival outcomes in 154 breast cancer patients with pulmonary metastasis in a real-world setting.Discover oncology · 2026Article
- Early Individualized Psychological Intervention Using Virtual Reality-assisted Decision System Reduces Decisional Conflict in Patients with Pulmonary Nodules: A Randomized Controlled Trial.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2026Article
- Differential diagnosis of benign and malignant pulmonary nodules attached to the interlobar pleura.Quantitative imaging in medicine and surgery · 2026Article
- The role of radiological imaging in differentiating malignant and benign pulmonary nodules: a retrospective study.BMC medical imaging · 2026Article
- Improving risk stratification of pulmonary nodules: an integrated perinodular vascular and radiomic model for clinical decision support.BMC medical imaging · 2026Article
- Relative leukocyte telomere length and the risk of lung cancer progression in individuals with pulmonary nodules.BMC medicine · 2026Article
- Article
- Independent Predictors Associated with Patient Refusal of Invasive Diagnostic Procedures After Positive LDCT Lung Cancer Screening.Diagnostics (Basel, Switzerland) · 2026Article
- Attention-Enhanced Hybrid Bidirectional LSTM and Temporal Convolutional Network for Early Detection of Lung Cancer in Low-Dose CT Scans.Biomedical engineering and computational biology · 2026Article
- Application of Nursing Intervention Under the Guidance of Enhanced Recovery After Surgery in Patients Who Underwent Pulmonary Nodules Resection.Journal of multidisciplinary healthcare · 2026Article
- Diagnostic accuracy of AI in chest radiography for pneumonia and lung cancer: A meta-analysis.European journal of radiology open · 2025Article
- Patient's knowledge, attitudes and behaviours towards pulmonary nodule management: a cross-sectional study in Wenzhou, China.BMJ open · 2025Article
- Single-Round LDCT Screening in Men Aged ≥ 70 Years: Prevalence of Pulmonary Nodules and Lung Cancer Detection.Cancers · 2025Article
- Intraoperative Lung Ultrasound in the Detection of Pulmonary Nodules: A Valuable Tool in Thoracic Surgery.Diagnostics (Basel, Switzerland) · 2025Review
- Diagnostic value of combined CT artificial intelligence (AI) system and lung cancer biomarkers in pulmonary nodule evaluation.AIMS public health · 2025Article
- Global burden of pulmonary sarcoidosis from 1990 to 2021: a comprehensive analysis based on the GBD 2021 study.Frontiers in medicine · 2025Article
Corrections and comments
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Authors and funding
8 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Background: Pulmonary nodules are small, focal lesions often identified via computed tomography (CT) scans. Although the majority are benign, a small percentage of them may be malignant or potentially become malignant, underscoring the importance of early detection and effective management. This study systematically reviews the epidemiology, risk factors, and management strategies for pulmonary nodules, comparing findings across Chinese and non-Chinese populations to better inform the actuarial calculations for predicting the demand of medical services for patients with pulmonary nodules. Methods: We performed a systematic analysis of the PubMed and China Knowledge Infrastructure (CNKI) databases for studies reporting the detection rate of pulmonary nodules through CT scans. Both cross-sectional studies and the baseline data from longitudinal studies were included. A modified version of the Newcastle-Ottawa Scale was used to assess the risk of bias and random effect models were used to estimate the overall prevalence. Results: We identified 32 studies and included 24 of them in our meta-analysis. Pooled analysis showed that the overall prevalence of pulmonary nodules was 0.27 (95% confidence interval: 0.25-0.29) after outliers removal. Subgroup analysis showed that there was no significant difference for prevalence between Chinese and non-Chinese populations. Males (0.38) were shown to have slightly higher prevalence compared to females (0.36), but not significant (P=0.88). Age and smoking are the most frequently reported risk factors by studies. Conclusions: Overall, 27% of participants were positive for pulmonary nodules. Advancing age and smoking were consistently identified as a key risk factor for the incidence of pulmonary nodules. Although the management strategies are different across studies, recent guidelines recommend personalized management strategies, prioritizing nodule size, characteristics, and individual risk factors to optimize outcomes.
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