Evidence map›Paper›PMID 39144271›Full record

ArticleReports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology2024

Design and performance validation of a novel 3d printed thin-walled and transparent electron beam applicators for intraoperative radiation therapy with beam energy up to 12 MeV.

Agnieszka Misiarz, Aleksandra Lenartowicz, Przemysław Adrich, Jacek Rzadkiewicz, Sławomir Wronka, Jan Trzuskowski, Marta Kruszyna-Mochalska, Bartosz Urbański, Beata Adamczyk, Jacek Pracz

Abstract read
In one paragraph

Article in Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Application of 3D printing for personalized boluses in radiotherapy: a systematic review.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Agnieszka MisiarzNational Centre for Nuclear Research, Otwock-Swierk, Poland.
Aleksandra LenartowiczNational Centre for Nuclear Research, Otwock-Swierk, Poland.
Przemysław AdrichNational Centre for Nuclear Research, Otwock-Swierk, Poland.
Jacek RzadkiewiczNational Centre for Nuclear Research, Otwock-Swierk, Poland.
Sławomir WronkaNational Centre for Nuclear Research, Otwock-Swierk, Poland.
Jan TrzuskowskiNational Centre for Nuclear Research, Otwock-Swierk, Poland.
Marta Kruszyna-MochalskaDepartment of Medical Physics, Greater Poland Cancer Centre, Poznan, Poland.
Bartosz UrbańskiDepartment of Electroradiology, Poznan University of Medical Sciences, Poznan, Poland.
Beata AdamczykDepartment of Breast Surgical Oncology, Greater Poland Cancer Centre, Poznan, Poland.
Jacek PraczCentre of High Technologies "HITEC ŚWIERK" Ltd, Otwock, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A high-energy electron accelerator is used in the treatment of patients in the so-called intraoperative electron radiotherapy (IOERT). The work aimed to present the results of the validation of a new design of an electron beam applicator for use in IOERT. A novel solution was described along with the design optimization method based on Monte Carlo simulations. In this solution, the applicator consists of two parts. The lower exchangeable part collimates the therapeutic field. Measurements were made based on the International Electrotechnical Commission (IEC) standard recommendations. The measurement described in the standard has been adapted to the specificity of the intraoperative accelerator Source to Skin Distance - of 60 cm and applicators with a circular cross-sectional area. Measurements were performed for nominal beam energies of 6, 10, and 12 MeV and two therapeutic field diameters of 6 and 10 cm. The dose due to stray X-ray radiation in all energies is less than 0.3% and increases for energies from 6 to 12 MeV by 2.9 times from 0.1 for 6MeV to 0.29 for 12 MeV. The average dose due to leakage radiation also shows an increasing trend and is higher for a 6 cm diameter applicator. Validation confirmed the usefulness of the novel applicator design for clinical applications. Thanks to the use of 3D printing, it was possible to make applicators that are transparent, biocompatible and, at the same time, light and form a beam field with therapeutically useful accuracy, and the leakage radiation does not exceed normative recommendations.

Indexed as

electron applicatorelectron linear acceleratorIOERT

Identifiers

PMID39144271
PMCPMC11321790

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.