Evidence map›Paper›PMID 39144229›Full record

ArticleFrontiers in microbiology2024

The Comparative Genome Dashboard.

Suzanne Paley, Ron Caspi, Paul O'Maille, Peter D Karp

Abstract read
In one paragraph

Article in Frontiers in microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Suzanne PaleyBioinformatics Research Group, SRI International, Menlo Park, CA, United States.
Ron CaspiBioinformatics Research Group, SRI International, Menlo Park, CA, United States.
Paul O'MailleBiosciences Division, SRI International, Menlo Park, CA, United States.
Peter D KarpBioinformatics Research Group, SRI International, Menlo Park, CA, United States.

Funding

Robust Software Components for Model Organism DatabasesR01GM075742 · NIGMS · SRI INTERNATIONAL · PI KARP, PETER D · 2005 to 2019
$12.0M
Development and Support of the Pathway Tools SoftwareR01AI160719 · NIAID · SRI INTERNATIONAL · PI PETER D KARP · 2021 to 2026
$5.9M
NIAID NIH HHS R01 AI160719NIGMS NIH HHS R01 GM075742
6 · The paper itself

Abstract

The Comparative Genome Dashboard is a web-based software tool for interactive exploration of the similarities and differences in gene functions between organisms. It provides a high-level graphical survey of cellular functions, and enables the user to drill down to examine subsystems of interest in greater detail. At its highest level the Comparative Dashboard contains panels for cellular systems such as biosynthesis, energy metabolism, transport, and response to stimulus. Each panel contains a set of bar graphs that plot the numbers of compounds or gene products for each organism across a set of subsystems of that panel. Users can interactively drill down to focus on subsystems of interest and see grids of compounds produced or consumed by each organism, specific GO term assignments, pathway diagrams, and links to more detailed comparison pages. For example, the dashboard enables users to compare the cofactors that a set of organisms can synthesize, the metal ions that they are able to transport, their DNA damage repair capabilities, their biofilm-formation genes, and their viral response proteins. The dashboard enables users to quickly perform comprehensive comparisons at varying levels of detail.

Indexed as

comparative functional profilescomparative genomicsfunctional traitsinference of metabolic capabilitiesmicrobial genome

Identifiers

PMID39144229
PMCPMC11322064

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.