ArticleFrontiers in microbiology2024
Identification of novel Tet(X6)-Tet(X2) recombinant variant in
Article in Frontiers in microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Molecular epidemiology and emergingAntimicrobial agents and chemotherapy · 2026Article
- From cognition to response: clinical challenges, antibiotic resistance mechanisms, and prevention and control strategies ofFrontiers in microbiology · 2026Review
- ICEAntibiotics (Basel, Switzerland) · 2025Article
- Genomic Diversity of theMicroorganisms · 2025Article
- Emergence of tigecycline-resistantFrontiers in microbiology · 2025Article
Corrections and comments
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Authors and funding
7 authors.
Funding
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Abstract
Introduction: The dissemination of strains producing tetracyclines monooxygenase Tet(X) from breeding farms to the natural environment poses a potential threat to public health. Methods: Antimicrobial susceptibility testing and WGS were performed to identify resistance phenotypes and genotypes. Cloning experiments, sequence alignment, and homology modeling were used to characterize the function and formation mechanisms of the recombinant variant. The mobilization potential of Tet(X) was assessed by collinearity analysis, conjugation experiments, and phylogenetic analysis. Results: Three Discussion: To our knowledge, this is the first report of homologous recombination between Tet(X) variants with differing activities. These clonal strains provide evidence of the transmission of
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