Evidence map›Paper›PMID 39144118›Full record

ArticleSchizophrenia bulletin open2024

Childhood Anxiety Symptoms as a Predictor of Psychotic Experiences in Adolescence in a High-Risk Cohort for Psychiatric Disorders.

Viviane Machado, Lais Fonseca, Matheus Ghossain Barbosa, Rodrigo A Bressan, Pedro Pan, Luis Augusto Rohde, Euripedes Constantino Miguel, Giovanni A Salum, Carolina Ziebold, Ary Gadelha

Abstract read
In one paragraph

Article in Schizophrenia bulletin open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Viviane MachadoDepartment of Psychiatry, Federal University of São Paulo, São Paulo, Brazil.ORCID https://orcid.org/0000-0003-0506-7370
Lais FonsecaDepartment of Psychiatry, Federal University of São Paulo, São Paulo, Brazil.ORCID https://orcid.org/0000-0003-2686-2752
Matheus Ghossain BarbosaDepartment of Psychiatry, Federal University of São Paulo, São Paulo, Brazil.ORCID https://orcid.org/0000-0002-3917-9445
Rodrigo A BressanDepartment of Psychiatry, Interdisciplinary Laboratory in Clinical Neuroscience (LiNC), Department of Psychiatry, Federal University of São Paulo, São Paulo, Brazil.
Pedro PanDepartment of Psychiatry, Interdisciplinary Laboratory in Clinical Neuroscience (LiNC), Department of Psychiatry, Federal University of São Paulo, São Paulo, Brazil.
Luis Augusto RohdeNational Institute of Developmental Psychiatry for Children and Adolescents (INCT-CNPq), São Paulo, Brazil.
Euripedes Constantino MiguelDepartment and Institute of Psychiatry (IPQ), University of São Paulo, São Paulo, Brazil.
Giovanni A SalumNational Institute of Developmental Psychiatry for Children and Adolescents (INCT-CNPq), São Paulo, Brazil.
Carolina ZieboldDepartment of Psychiatry, Federal University of São Paulo, São Paulo, Brazil.
Ary GadelhaDepartment of Psychiatry, Federal University of São Paulo, São Paulo, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Hypothesis: When occurring in adolescence, psychotic experiences (PE), subclinical psychotic symptoms, can be an early marker of mental illnesses. Studies with high-risk populations for psychosis show that anxiety symptoms often precede the onset of psychosis. Although anxiety symptoms are frequently experienced across the continuum of psychosis, no previous study has analyzed this association using a cross-lagged panel model (CLPM) longitudinally to identify if anxiety can be a predictor of PE over time or vice versa. The aim of the current study was to investigate whether one symptom domain predicts the other over time. Study Design: 2194 children from the Brazilian High-Risk Cohort (BHRC) were evaluated at baseline ( Study Results: Higher levels of anxiety in childhood predicted an increase in PE levels in adolescence. The cross-lagged effect of anxiety scores at Conclusions: Our findings reinforce that anxiety may represent an early marker of psychosis proneness, not a consequence of already presenting PE, which can help to develop better screening approaches. Therefore, future studies should focus on identifying biological or other clinical markers to increase prediction accuracy.

Indexed as

attenuated psychotic symptomscross-lagged panel modelsdevelopmental psychopathologyearly diagnosispsychosis early markers

Identifiers

PMID39144118
PMCPMC11207689

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.