Evidence map›Paper›PMID 39144116›Full record

ArticleSchizophrenia bulletin open2024

Current Auditory Hallucinations Are Not Associated With Specific White Matter Diffusion Alterations in Schizophrenia.

Stener Nerland, Nora Berz Slapø, Claudia Barth, Lynn Mørch-Johnsen, Kjetil Nordbø Jørgensen, Dani Beck, Laura A Wortinger, Lars T Westlye, Erik G Jönsson, Ole A Andreassen and 3 more

Abstract read
In one paragraph

Article in Schizophrenia bulletin open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Stener NerlandDepartment of Psychiatric Research, Diakonhjemmet Hospital, Oslo, Norway.ORCID https://orcid.org/0000-0001-8771-8856
Nora Berz SlapøNorwegian Center for Mental Disorders Research (NORMENT), Institute of Clinical Medicine, University of Oslo, Oslo, Norway.ORCID https://orcid.org/0000-0001-9360-8610
Claudia BarthDepartment of Psychiatric Research, Diakonhjemmet Hospital, Oslo, Norway.ORCID https://orcid.org/0000-0001-6544-0945
Lynn Mørch-JohnsenNorwegian Center for Mental Disorders Research (NORMENT), Institute of Clinical Medicine, University of Oslo, Oslo, Norway.ORCID https://orcid.org/0000-0002-0185-3713
Kjetil Nordbø JørgensenNorwegian Center for Mental Disorders Research (NORMENT), Institute of Clinical Medicine, University of Oslo, Oslo, Norway.ORCID https://orcid.org/0000-0002-5751-4809
Dani BeckDepartment of Psychiatric Research, Diakonhjemmet Hospital, Oslo, Norway.ORCID https://orcid.org/0000-0002-0974-9304
Laura A WortingerDepartment of Psychiatric Research, Diakonhjemmet Hospital, Oslo, Norway.ORCID https://orcid.org/0000-0003-2721-3172
Lars T WestlyeNorwegian Center for Mental Disorders Research (NORMENT), Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.ORCID https://orcid.org/0000-0001-8644-956X
Erik G JönssonNorwegian Center for Mental Disorders Research (NORMENT), Institute of Clinical Medicine, University of Oslo, Oslo, Norway.ORCID https://orcid.org/0000-0001-8368-6332
Ole A AndreassenDepartment of Psychiatric Research, Diakonhjemmet Hospital, Oslo, Norway.ORCID https://orcid.org/0000-0002-4461-3568
Ivan I MaximovNorwegian Center for Mental Disorders Research (NORMENT), Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.ORCID https://orcid.org/0000-0001-6319-6774
Oliver M GeierDepartment of Computational Radiology and Physics, Division of Radiology and Nuclear Medicine, Oslo University Hospital, Oslo, Norway.ORCID https://orcid.org/0000-0003-3919-7579
Ingrid AgartzDepartment of Psychiatric Research, Diakonhjemmet Hospital, Oslo, Norway.ORCID https://orcid.org/0000-0002-9839-5391

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Hypothesis: Studies have linked auditory hallucinations (AH) in schizophrenia spectrum disorders (SCZ) to altered cerebral white matter microstructure within the language and auditory processing circuitry (LAPC). However, the specificity to the LAPC remains unclear. Here, we investigated the relationship between AH and DTI among patients with SCZ using diffusion tensor imaging (DTI). Study Design: We included patients with SCZ with (AH+; Study Results: Widespread differences relative to controls were observed for MD and RD in patients without current AH. Only limited differences in 2 fiber tracts were observed between AH+ and controls. Unimodal PCA factors based on MD, RD, and AD, as well as multimodal PCA factors, differed significantly relative to controls for AH-, but not AH+. We did not find any significant associations between PCA factors and clinical characteristics. Conclusions: Contrary to previous studies, DTI metrics differed mainly in patients

Indexed as

dimensionality reductionmagnetic resonance imagingprobabilistic tractographypsychotic disorderswhite matter microstructure

Identifiers

PMID39144116
PMCPMC11207682

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.