Evidence map›Paper›PMID 39143964›Full record

ArticleReports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology2024

The impact of XPC gene single nucleotide polymorphism rs2228001 on head and neck cancer patients' response to radiotherapy treatment.

Bartosz Maćkowiak, Kamila Ostrowska, Katarzyna Kulcenty, Joanna Kaźmierska, Julia Ostapowicz, Hanna Nowicka, Mateusz Szewczyk, Krzysztof Książek, Wiktoria M Suchorska, Wojciech Golusiński

Abstract read
In one paragraph

Article in Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Biomedicines · 2026
    Article
  2. Article
  3. lncRNA EGOT across cancers: TCGA analysis.Archives of medical science : AMS · 2026
    Article
  4. Article
  5. lncRNABiomedicines · 2025
    Article
  6. Review
  7. Nucleus Accumbens Associated Protein 1 in Cancers-The Real Value.International journal of molecular sciences · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Bartosz MaćkowiakDepartment of Head and Neck Surgery, Poznan University of Medical Sciences, Poznan, Poland.
Kamila OstrowskaDepartment of Head and Neck Surgery, Poznan University of Medical Sciences, Poznan, Poland.
Katarzyna KulcentyRadiobiology Laboratory, The Greater Poland Cancer Centre, Poznan, Poland.
Joanna KaźmierskaRadiotherapy Department II, The Greater Poland Cancer Centre, Poznan, Poland.
Julia OstapowiczDepartment of Head and Neck Surgery, Poznan University of Medical Sciences, Poznan, Poland.
Hanna NowickaFaculty of Medicine, Poznan University of Medical Sciences, Poznan, Poland.
Mateusz SzewczykDepartment of Head and Neck Surgery, Poznan University of Medical Sciences, Poznan, Poland.
Krzysztof KsiążekDepartment of Pathophysiology of Ageing and Civilization Diseases, Poznan University of Medical Sciences, Poznan, Poland.
Wiktoria M SuchorskaRadiobiology Laboratory, The Greater Poland Cancer Centre, Poznan, Poland.
Wojciech GolusińskiDepartment of Head and Neck Surgery, Poznan University of Medical Sciences, Poznan, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Head and neck squamous carcinoma (HNSC) is the sixth most common neoplasm, with a 40-50% overall survival rate. HNSC standard treatment depends on tumor size, metastasis or human papillomavirus (HPV) status including surgery, chemotherapy, and radiotherapy. The last two may lead to defects in the tumor microenvironment and cancer cell biology as disorders in DNA damage repair systems. Here, we evaluate the correlation between single nucleotide polymorphism (SNP) rs2228001 in the Materials and methods: Head and neck cancer tissues and clinical data were obtained from 79 patients. The SNP of the Results/Conclusion: Single nucleotide polymorphism rs2228001 in the

Indexed as

adverse effectsdamage repair systemshead and neck cancerradiotherapyXPC

Identifiers

PMID39143964
PMCPMC11321765

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.