Evidence map›Paper›PMID 39143870›Full record

ArticleCurrent Alzheimer research2024

Dysregulation of

Asma Hamdi, Sana Baroudi, Alya Gharbi, Wafa Babay, Ahmed Baligh Laaribi, Imene Kacem, Saloua Mrabet, Ines Zidi, Naouel Klibi, Riadh Gouider and 1 more

Abstract read
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In one paragraph

Article in Current Alzheimer research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Asma HamdiLaboratory of Microorganisms and Active Biomolecules (LR03ES03), Faculty of Sciences of Tunis, University of Tunis El Manar, Campus Universitaire 2092, Tunis, Tunisia.
Sana BaroudiLaboratory of Microorganisms and Active Biomolecules (LR03ES03), Faculty of Sciences of Tunis, University of Tunis El Manar, Campus Universitaire 2092, Tunis, Tunisia.
Alya GharbiNeurology Department, Razi University Hospital, Manouba, Tunisia.
Wafa BabayLaboratory of Microorganisms and Active Biomolecules (LR03ES03), Faculty of Sciences of Tunis, University of Tunis El Manar, Campus Universitaire 2092, Tunis, Tunisia.
Ahmed Baligh LaaribiLaboratory of Microorganisms and Active Biomolecules (LR03ES03), Faculty of Sciences of Tunis, University of Tunis El Manar, Campus Universitaire 2092, Tunis, Tunisia.
Imene KacemNeurology Department, Razi University Hospital, Manouba, Tunisia.
Saloua MrabetNeurology Department, Razi University Hospital, Manouba, Tunisia.
Ines ZidiLaboratory of Microorganisms and Active Biomolecules (LR03ES03), Faculty of Sciences of Tunis, University of Tunis El Manar, Campus Universitaire 2092, Tunis, Tunisia.
Naouel KlibiLaboratory of Microorganisms and Active Biomolecules (LR03ES03), Faculty of Sciences of Tunis, University of Tunis El Manar, Campus Universitaire 2092, Tunis, Tunisia.
Riadh GouiderNeurology Department, Razi University Hospital, Manouba, Tunisia.
Hadda-Imene OuzariLaboratory of Microorganisms and Active Biomolecules (LR03ES03), Faculty of Sciences of Tunis, University of Tunis El Manar, Campus Universitaire 2092, Tunis, Tunisia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlzheimer's disease (AD) is the most prevalent neurodegenerative disorder, with a significant burden on global health. AD is characterized by a progressive cognitive decline and memory loss. Emerging research suggests a potential link between periodontitis, specifically the presence of oral bacteria such as

objectiveThis study aims to investigate the dysregulation of

methodsSaliva samples were collected from a total of 54 individuals, including 27 AD patients and 27 healthy controls. The expression of the

resultsThe results showed a significant decrease in

conclusionThese findings suggest that measuring

Indexed as

Alzheimer DiseaseBacteroidaceae InfectionsBiomarkersHydrolasesPeriodontitisPorphyromonas gingivalisAgedAged, 80 and overCase-Control StudiesDisease ProgressionEarly DiagnosisFemaleGene ExpressionHumansMaleMiddle Agedagmatine deiminaseBiomarkersHydrolasesAlzheimer’s diseaseargininePeriodontitispolyamines metabolismPorphyromonas gingivalissaliva.

Identifiers

PMID39143870

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.