Evidence map›Paper›PMID 39143731›Full record

ArticleEquine veterinary journal2025

Comparison of radiography and computed tomography for identification of third metacarpal structural change and associated assessment of condylar stress fracture risk in Thoroughbred racehorses.

Soroush Irandoust, Linnea M O'Neil, Christina M Stevenson, Faith M Franseen, Pieter H L Ramzan, Sarah E Powell, Sabrina H Brounts, Samantha J Loeber, David L Ergun, R Chris Whitton and 2 more

Abstract readComparative Study
In one paragraph

Article in Equine veterinary journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Correlation of 2D Linear and 3D Volumetric Measurement Techniques for Subchondral Bone Sclerosis in the Equine Distal Limb Using Standing Computed Tomography.Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Soroush IrandoustDepartment of Surgical Sciences, University of Wisconsin-Madison, Madison, Wisconsin, USA.ORCID https://orcid.org/0000-0001-9937-1204
Linnea M O'NeilDepartment of Surgical Sciences, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Christina M StevensonDepartment of Surgical Sciences, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Faith M FranseenDepartment of Surgical Sciences, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Pieter H L RamzanRossdales Veterinary Surgeons, Newmarket, UK.ORCID https://orcid.org/0000-0001-5854-5650
Sarah E PowellVetCT, Cambridge, UK.
Sabrina H BrountsDepartment of Surgical Sciences, University of Wisconsin-Madison, Madison, Wisconsin, USA.ORCID https://orcid.org/0000-0001-8748-7912
Samantha J LoeberDepartment of Surgical Sciences, University of Wisconsin-Madison, Madison, Wisconsin, USA.ORCID https://orcid.org/0000-0003-4921-2357
David L ErgunAsto CT, 7921 UW Health Ct., Middleton, Wisconsin, USA.
R Chris WhittonDepartment of Veterinary Clinical Sciences, Melbourne Veterinary School, Faculty of Science, University of Melbourne, Werribee, Victoria, Australia.ORCID https://orcid.org/0000-0003-0012-4065
Corinne R HenakDepartment of Mechanical Engineering, University of Wisconsin-Madison, Madison, Wisconsin, USA.ORCID https://orcid.org/0000-0002-1525-1350
Peter MuirDepartment of Surgical Sciences, University of Wisconsin-Madison, Madison, Wisconsin, USA.ORCID https://orcid.org/0000-0003-0028-6005

Funding

Grayson-Jockey Club Research Foundation
6 · The paper itself

Abstract

backgroundCatastrophic injury has a low incidence but leads to the death of many Thoroughbred racehorses.

objectivesTo determine sensitivity, specificity, and reliability for third metacarpal condylar stress fracture risk assessment from digital radiographs (DR) and standing computed tomography (sCT). STUDY

designControlled ex vivo experiment.

methodsA blinded set of metacarpophalangeal joint DR and sCT images were prepared from 31 Thoroughbreds. Four observers evaluated the condyles and parasagittal grooves (PSG) of the third metacarpal bone for the extent of dense bone and lucency/fissure and assigned a risk assessment grade for condylar stress fracture based on imaging features. Sensitivity and specificity for detection of subchondral structural changes in the condyles and PSG, and for risk assessment for condylar stress fracture were determined by comparison with a reference assessment based on sCT and joint surface examination. Agreement between observers and the reference assessment and reliability between observers were determined. Intra-observer repeatability was also assessed.

resultsSensitivity for detection of structural change was lower than specificity for both imaging methods and all observers. For agreement with the reference assessment of structural change, correlation coefficients were generally below 0.5 for DR and 0.49-0.82 for sCT. For horses categorised as normal risk on reference assessment, observer assessment often agreed with the reference. Sensitivity for risk assessment was lower than specificity for all observers. For horses with a reference assessment of high risk of injury, observers generally underestimated risk. Diagnostic sensitivity of risk assessment was improved with sCT imaging, particularly for horses categorised as having elevated risk of injury from the reference assessment. Assessment repeatability and reliability was better with sCT than DR. MAIN LIMITATIONS: The ex vivo study design influenced DR image sets.

conclusionsRisk assessment through screening with diagnostic imaging is a promising approach to improve injury prevention in racing Thoroughbreds. Knowledge of sensitivity and specificity of fetlock lesion detection provides the critical guidance needed to improve racehorse screening programs. We found improved detection of MC3 subchondral structural change and risk assessment for condylar stress fracture with sCT ex vivo.

Indexed as

Fractures, StressHorse DiseasesMetacarpal BonesRadiographyTomography, X-Ray ComputedAnimalsFemaleForelimbHorsesMaleSensitivity and Specificitycondylar stress fracturedigital radiographyfetlockhorseracing Thoroughbredstanding computed tomography

Identifiers

PMID39143731
PMCPMC11982434

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.