Evidence map›Paper›PMID 39143147›Full record

ArticleNature communications2024

A concentration of visual cortex-like neurons in prefrontal cortex.

Olivia Rose, Carlos R Ponce

Abstract read
In one paragraph

Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. The cost of efficiency in flexible neural representations.bioRxiv : the preprint server for biology · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Olivia RoseDepartment of Neurobiology, Harvard Medical School, Boston, MA, USA.ORCID 0000-0003-1762-2829
Carlos R PonceDepartment of Neurobiology, Harvard Medical School, Boston, MA, USA. carlos_ponce@hms.harvard.edu.ORCID 0000-0002-9887-3234

Funding

Viral ModuleP30EY012196 · NEI · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI MARGARET S LIVINGSTONE · 1998 to 2026
$21.3M
Research Training Program in the Vision SciencesT32EY013360 · NEI · WASHINGTON UNIVERSITY · PI SHIMING CHEN, Daniel Kerschensteiner · 2000 to 2026
$5.6M
Defining mechanisms for natural vision in the primate brain with machine learningDP2EY035176 · NEI · HARVARD MEDICAL SCHOOL · PI PONCE, CARLOS RAMON · 2022 to 2025
$2.5M
The stability of visual representations in the primate ventrolateral prefrontal cortexF31EY034784 · NEI · HARVARD MEDICAL SCHOOL · PI BOCKLER, OLIVIA ROSE · 2023 to 2023
$34k
David and Lucile Packard Foundation (David & Lucile Packard Foundation) 2021-73455NEI NIH HHS DP2 EY035176NEI NIH HHS F31 EY034784NEI NIH HHS P30 EY012196NEI NIH HHS T32 EY013360U.S. Department of Health & Human Services | National Institutes of Health (NIH) 1DP2EY035176-01U.S. Department of Health & Human Services | National Institutes of Health (NIH) EY034784
6 · The paper itself

Abstract

Visual recognition is largely realized through neurons in the ventral stream, though recently, studies have suggested that ventrolateral prefrontal cortex (vlPFC) is also important for visual processing. While it is hypothesized that sensory and cognitive processes are integrated in vlPFC neurons, it is not clear how this mechanism benefits vision, or even if vlPFC neurons have properties essential for computations in visual cortex implemented via recurrence. Here, we investigated if vlPFC neurons in two male monkeys had functions comparable to visual cortex, including receptive fields, image selectivity, and the capacity to synthesize highly activating stimuli using generative networks. We found a subset of vlPFC sites show all properties, suggesting subpopulations of vlPFC neurons encode statistics about the world. Further, these vlPFC sites may be anatomically clustered, consistent with fMRI-identified functional organization. Our findings suggest that stable visual encoding in vlPFC may be a necessary condition for local and brain-wide computations.

Indexed as

Macaca mulattaMagnetic Resonance ImagingNeuronsPrefrontal CortexVisual CortexAnimalsBrain MappingMalePhotic StimulationVisual Perception

Identifiers

PMID39143147
PMCPMC11324908

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.