Evidence map›Paper›PMID 39143076›Full record

ArticleNutrition & diabetes2024

Identification of interactions between genetic risk scores and dietary patterns for personalized prevention of kidney dysfunction in a population-based cohort.

Min-Jae Jang, Li-Juan Tan, Min Young Park, Sangah Shin, Jun-Mo Kim

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In one paragraph

Article in Nutrition & diabetes, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. The Role of Precision Nutrition in Kidney Disease.Clinical journal of the American Society of Nephrology : CJASN · 2026
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Min-Jae JangDepartment of Animal Science and Technology, Chung-Ang University, Gyeonggi-do, 17546, Korea.
Li-Juan TanDepartment of Food and Nutrition, Chung-Ang University, Gyeonggi-do, 17546, Korea.ORCID 0000-0002-8970-0884
Min Young ParkDepartment of Molecular Pathobiology, NYU College of Dentistry, New York, USA.
Sangah ShinDepartment of Food and Nutrition, Chung-Ang University, Gyeonggi-do, 17546, Korea. ivory8320@cau.ac.kr.ORCID 0000-0003-0094-1014
Jun-Mo KimDepartment of Animal Science and Technology, Chung-Ang University, Gyeonggi-do, 17546, Korea. junmokim@cau.ac.kr.ORCID 0000-0002-6934-398X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND &

aimChronic kidney disease (CKD) is a heterogeneous disorder that affects the kidney structure and function. This study investigated the effect of the interaction between genetic factors and dietary pattern on kidney dysfunction in Korean adults.

methodsBaseline data were obtained from the Ansan and Ansung Study of the Korean Genome and Epidemiology Study involving 8230 participants aged 40-69 years. Kidney dysfunction was defined as an estimated glomerular filtration rate < 90 mL/minute/1.73 m

resultsThree distinct dietary patterns were extracted, namely, the "prudent pattern," "flour-based and animal food pattern," and "white rice pattern," to analyze the effect of dietary pattern on kidney function. In the "flour-based and animal food pattern," higher pattern scores were associated with a higher prevalence of kidney dysfunction in both the low and high GR groups (P for trend < 0.0001 in the low-, high-GR groups of model 1; 0.0050 and 0.0065 in the low-, high-GR groups of model 2, respectively).

conclusionsThe results highlight a significant association between the 'flour-based and animal food pattern' and higher kidney dysfunction prevalence in individuals with both low and high GR. These findings suggest that personalized nutritional interventions based on GR profiles may become the basis for presenting GR-based individual dietary patterns for kidney dysfunction.

Indexed as

DietGenome-Wide Association StudyGlomerular Filtration RatePolymorphism, Single NucleotideRenal Insufficiency, ChronicAdultAgedCohort StudiesFemaleGenetic Predisposition to DiseaseGenetic Risk ScoreHumansMaleMiddle AgedRepublic of KoreaRisk Factors

Identifiers

PMID39143076
PMCPMC11325018

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.