ArticleJournal of child psychology and psychiatry, and allied disciplines2025
Mapping associations of polygenic scores with autistic and ADHD traits in a single city region.
Article in Journal of child psychology and psychiatry, and allied disciplines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- A comprehensive overview of the biological foundations of ADHD.Bioscience reports · 2026Review
- Global Statistics of Attention-Deficit/Hyperactivity Disorder, Autism Spectrum Disorder, and Conduct Disorder among School-Age Children from 1990-2021, with Forecasts to 2040.Neuroepidemiology · 2026Article
- Where you live matters: visualizing environmental effects on reading attainment.Journal of child psychology and psychiatry, and allied disciplines · 2024Article
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Authors and funding
9 authors.
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Abstract
backgroundThe genetic and environmental aetiology of autistic and Attention Deficit Hyperactivity Disorder (ADHD) traits is known to vary spatially, but does this translate into variation in the association of specific common genetic variants?
methodsWe mapped associations between polygenic scores for autism and ADHD and their respective traits in the Avon Longitudinal Study of Parents and Children (N = 4,255-6,165) across the area surrounding Bristol, UK, and compared them to maps of environments associated with the prevalence of autism and ADHD.
resultsOur results suggest genetic associations vary spatially, with consistent patterns for autistic traits across polygenic scores constructed at different p-value thresholds. Patterns for ADHD traits were more variable across thresholds. We found that the spatial distributions often correlated with known environmental influences.
conclusionsThese findings shed light on the factors that contribute to the complex interplay between the environment and genetic influences in autistic and ADHD traits.
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