Evidence map›Paper›PMID 39143016›Full record

ArticleThe Journal of veterinary medical science2024

Aquaporin 3 is expressed in the basaloid cells of canine sebaceous glands.

Hiroko Sonoda, Yoshiki Taniguchi, Naruki Fujimoto, Yoshiki Higashijima, Toshiyuki Matsuzaki, Takuya Hirai, Teruo Itoh, Kazuyuki Uchida, Masahiro Ikeda

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of veterinary medical science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hiroko SonodaDepartment of Veterinary Pharmacology, University of Miyazaki, Miyazaki, Japan.
Yoshiki TaniguchiDepartment of Veterinary Pharmacology, University of Miyazaki, Miyazaki, Japan.
Naruki FujimotoDepartment of Veterinary Pharmacology, University of Miyazaki, Miyazaki, Japan.
Yoshiki HigashijimaInstitute for Promotion of Tenure Track, University of Miyazaki, Miyazaki, Japan.
Toshiyuki MatsuzakiDepartment of Anatomy and Cell Biology, Gunma University Graduate School of Medicine, Gunma, Japan.
Takuya HiraiDepartment of Veterinary Pathology, University of Miyazaki, Miyazaki, Japan.
Teruo ItohDivision of Animal Medical Research, Hassen-kai, Miyazaki, Japan.
Kazuyuki UchidaLaboratory of Veterinary Pathology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan.
Masahiro IkedaDepartment of Veterinary Pharmacology, University of Miyazaki, Miyazaki, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The role of aquaporin proteins (AQPs) in tumor biology has attracted attention over the past 20 years. However, the expression profiles of AQPs in canine sebaceous gland tumors remain obscure. This study was performed to clarify the expression of AQP1, 3, 5, the most studied AQPs in tumor biology, in sebaceous adenoma and sebaceous epithelioma. Among these AQPs, only AQP3 was expressed in normal tissue and both tumor types and located to only undifferentiated sebocytes (basaloid cells). A cellular proliferation marker, Ki-67, was detected only in the area including basaloid cells in both tumor types. These findings suggest that AQP3 is useful for clarifying the origin of sebaceous gland tumors, and that AQP3 may be related to sebaceous gland development.

Indexed as

AdenomaAquaporin 3Dog DiseasesSebaceous Gland NeoplasmsSebaceous GlandsAnimalsDogsKi-67 AntigenMaleAquaporin 3Ki-67 Antigenaquaporin 3basaloid cellssebaceous adenomasebaceous epitheliomaundifferentiated sebocytes

Identifiers

PMID39143016
PMCPMC11442393

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.