ArticleOrthopaedic surgery2024
Prognostic Nutritional Index (PNI) as an Independent Predictor of 3-Year Postoperative Mortality in Elderly Patients with Hip Fracture: A Post hoc Analysis of a Prospective Cohort Study.
Article in Orthopaedic surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
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Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Association of multidimensional biomarkers of immune, nutritional, inflammatory, and metabolic status with postoperative outcomes in older hip fracture patients: a systematic review and meta-analysis.Frontiers in nutrition · 2026Pooled it
- Predictive value of prognostic nutritional index for the long-term prognosis of elderly patients with fracture: a systematic review and meta-analysis.Frontiers in nutrition · 2025Pooled it
- Comparison of the NUTRIC-PNI score and NUTRIC score to assess nutritional risk and predict 28-day mortality in critically ill patients: a prospective cohort study in Vietnam.Acute and critical care · 2026Article
- Comparative predictive performance of HALP score and prognostic nutritional index for mortality in ICU patients after hip fracture surgery.BMC geriatrics · 2026Article
- Nutritional Risk Scores and Cognitive Impairment After Hip Fracture: Strong Associations with Mortality but Limited Discriminative Performance.Nutrients · 2026Article
- The association between the geriatric nutritional risk index (GNRI) and postoperative outcomes after hip fracture in older adults: a prospective cohort study.BMC geriatrics · 2026Observational
- Prognostic Value of HALP Score, PNI, and SII in Predicting 1-Year Mortality in Geriatric Femoral Fractures: A 5-Year Emergency Department Cohort Study.Medical science monitor : international medical journal of experimental and clinical research · 2026Article
- Predicting 90-Day Mortality After Geriatric Hip Fracture Using Combined Preoperative and Perioperative Risk Factors.Geriatric orthopaedic surgery & rehabilitation · 2026Article
- Blood urea nitrogen to albumin ratio and 1-year mortality after hip fracture surgery in older adults: a retrospective cohort study.Frontiers in medicine · 2026Article
- Nutrition-related clinical laboratory indicators in perioperative management of geriatric hip fractures: a narrative review from risk stratification to precision intervention.Frontiers in nutrition · 2026Review
- Combining GNRI and CLR index predicts outcome following hip fracture surgery.Journal of bone and mineral metabolism · 2026Article
- A retrospective analysis of the link between the prognostic nutritional index and 1-year mortality rates in older adults suffering from femoral neck fractures.Frontiers in nutrition · 2026Article
- Rheumatoid arthritis-associated interstitial lung disease: clinical predictive model and external validation.Respiratory research · 2025Article
- Modified Frailty Index-11-A New Predictor of Postoperative Complications in the Aging Thoracic Spinal Stenosis Patients.Orthopaedic surgery · 2025Article
- Observational
- Relationship between mortality and HALP score in femoral neck fractures treated with hemiarthroplasty.Joint diseases and related surgery · 2025Article
- Enhancing Perioperative Oral Nutritional Supplements in Elderly Hip Fracture Patients: A Pilot Project on Evidence-Based Practice.Clinical interventions in aging · 2025Article
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11 authors.
Funding
Abstract
objectiveThe prognostic nutritional index (PNI) has been reported as a significant predictor in various diseases. However, the prognostic value of the PNI in geriatric hip fracture patients has not been thoroughly evaluated. This study aimed to investigate the association between admission PNI and 3-year mortality in those patients.
methodsIn this post hoc analysis, we included patients aged ≥65 years who underwent surgery for hip fracture between 2018 and 2019. The admission PNI was calculated as serum albumin (g/L) +5 × total lymphocyte count (×10
resultsOf the 942 eligible patients, 190 (20.2%) patients died during the follow-up. Compared to patients in the first quartile (Q1), those in the second (Q2), third (Q3), and fourth (Q4) quartiles had significantly lower mortality risks (HRs 0.50, 95% CI 0.35-0.74; 0.41, 95% CI 0.26-0.64; and 0.26, 95% CI 0.15-0.45, respectively). The optimal cutoff of PNI for predicting mortality was set as 45.275 (sensitivity, 0.674; specificity, 0.692; area under the curve (AUC), 0.727). Patients with higher PNI (>45.275) had a significant lower mortality risk (HR 0.39, 95% CI 0.28-0.55) compared to those with lower PNI (≤ 45.275).
conclusionPNI is a reliable and independent predictor of 3-year mortality after hip fracture surgery in the elderly.
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