Evidence map›Paper›PMID 39142590›Full record

ArticleJournal of affective disorders2024

Predictors of psychosocial impairment in a transdiagnostic sample: Unique effects of repetitive negative thinking.

Alexandra M Adamis, Julia G Lebovitz, Lauren Oberlin, Serena Chen, Dustin Phan, Katharine C Burns, Faith M Gunning, Katherine E Burdick

Abstract read
In one paragraph

Article in Journal of affective disorders, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Alexandra M AdamisVanderbilt University, 111 21(st) Avenue South, Nashville, TN 37203, USA.
Julia G LebovitzVanderbilt University, 111 21(st) Avenue South, Nashville, TN 37203, USA.
Lauren OberlinJoan & Sanford I. Weill Medical College of Cornell University, 525 East 68th Street, New York, NY 10065, USA.
Serena ChenJoan & Sanford I. Weill Medical College of Cornell University, 525 East 68th Street, New York, NY 10065, USA.
Dustin PhanJoan & Sanford I. Weill Medical College of Cornell University, 525 East 68th Street, New York, NY 10065, USA.
Katharine C BurnsBrigham and Women's Hospital, 221 Longwood Ave, Boston, MA 02115, USA.
Faith M GunningJoan & Sanford I. Weill Medical College of Cornell University, 525 East 68th Street, New York, NY 10065, USA.
Katherine E BurdickBrigham and Women's Hospital, 221 Longwood Ave, Boston, MA 02115, USA; Harvard Medical School, Boston, MA, USA. Electronic address: kburdick1@bwh.harvard.edu.

Funding

Clinical and Translational Science AwardUL1TR001873 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI REILLY, MUREDACH P · 2016 to 2025
$99.0M
Disparities in COVID Disease Severity and Outcomes in New York CityUL1TR002384 · NCATS · WEILL MEDICAL COLL OF CORNELL UNIV · PI JULIANNE L IMPERATO-MCGINLEY · 2017 to 2026
$86.2M
Brain-based Mechanisms of Emotion Regulation in Aging and Mood DisordersR01MH124381 · NIMH · BRIGHAM AND WOMEN'S HOSPITAL · PI BURDICK, KATHERINE ELIZABETH, GUNNING, FAITH M · 2021 to 2025
$4.1M
NCATS NIH HHS UL1 TR001873NCATS NIH HHS UL1 TR002384NIMH NIH HHS R01 MH124381
6 · The paper itself

Abstract

backgroundRepetitive negative thinking (RNT) is a transdiagnostic process involving perseverative, unproductive, and uncontrollable thoughts. Although RNT may impede adaptive psychosocial functioning by prolonging negative mood states, strengthening cognitive biases, and preventing effective problem-solving, the extent to which RNT is associated with risk for poor psychosocial outcomes is unclear. Given that this has clear transdiagnostic treatment implications, the present study aimed to isolate the unique relationship of RNT with social functioning and life satisfaction in a mixed clinical and non-clinical sample.

methodsIn 201 mid-to-later life adult participants (27 with primary diagnoses of bipolar disorder, 84 with major depressive disorder, and 90 healthy volunteers), we measured RNT, social functioning, life satisfaction, trait rumination, DSM-5 diagnoses, depressive symptoms, manic symptoms, cognitive control performance, and global cognitive functioning.

resultsLinear regression models revealed that RNT, but not rumination, was significantly associated with poorer social functioning (β = 0.42 p < .001) and reduced life satisfaction (β = -0.42, p < .001) after controlling for clinical and cognitive covariates. LIMITATIONS: Limited demographic diversity, cross-sectional design, self-reporting of outcomes.

conclusionsResults suggest that RNT may confer risk for key psychosocial outcomes during middle to later adulthood, over and above the effects of clinical and cognitive variables and independent of diagnostic status. Findings lend support to the notion of RNT as a transdiagnostic process and suggest that RNT may be an important therapeutic target for adults with poor social functioning and/or reduced life satisfaction.

Indexed as

Bipolar DisorderMajor Depressive DisorderPersonal SatisfactionPsychosocial FunctioningRumination, CognitiveAdultAgedCross-Sectional StudiesFemaleHumansMaleMiddle AgedPessimismBipolar disorderCognitionDisabilityMajor depressive disorderRepetitive negative thinkingRumination

Identifiers

PMID39142590
PMCPMC11894607

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.