Evidence map›Paper›PMID 39142517›Full record

ArticleJournal of vascular and interventional radiology : JVIR2024

Feasibility and Safety of Lateral and Posterolateral Percutaneous Vertebroplasty of Osteolytic C1-C2 Lesions under Computed Tomography Guidance and Local Anesthesia.

Sylvain Guinebert, Georges Hayek, Francois H Cornelis, Federico Torre, Adrian Kastler, Nicolas Stacoffe, Nicolas Amoretti, Sylvain Bodard, Bruno Kastler

Abstract read
In one paragraph

Article in Journal of vascular and interventional radiology : JVIR, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sylvain GuinebertDepartment of Radiology, European Georges Pompidou Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France; Weill Cornell Medical College, New York, New York. Electronic address: sylvain.guinebert@outlook.com.
Georges HayekDepartment of Radiology, European Georges Pompidou Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France.
Francois H CornelisDepartment of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York; Weill Cornell Medical College, New York, New York.
Federico TorreDepartment of Radiology, Pasteur 2 Hospital, University Hospital Center of Nice, Nice, France.
Adrian KastlerDepartment of Radiology Grenoble University Hospital, Grenoble, France.
Nicolas StacoffeDepartment of Radiology, Groupement Hospitalier Sud, Hospices Civils de Lyon, Pierre-Bénite, France; Université Claude Bernard Lyon 1, Villeurbanne, France.
Nicolas AmorettiDepartment of Radiology, Pasteur 2 Hospital, University Hospital Center of Nice, Nice, France.
Sylvain BodardDepartment of Radiology, Necker Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France; Weill Cornell Medical College, New York, New York; Sorbonne University, CNRS UMR 7371, INSERM U 1146, Laboratoire d'Imagerie Biomédicale, Paris, France.
Bruno KastlerDepartment of Radiology, Necker Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France; Department of Radiology, European Georges Pompidou Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

purposeTo evaluate the safety and effectiveness of lateral or posterolateral percutaneous vertebroplasty (PVP) of osteolytic C1-C2 lesions performed under computed tomography (CT) guidance and local anesthesia. MATERIALS AND

methodsA retrospective study of 16 consecutive patients (11 females and 5 males; aged from 24 to 86 years; median age, 65.5 years) who underwent 17 lateral or posterolateral PVP was performed. Pain status was assessed using a visual analog scale (VAS). Patients were evaluated preprocedurally as baseline and at 24 hours and 1, 6, and 12 months postprocedurally, until death, or until loss to follow-up. The Oswestry Disability Index was used to evaluate the patients' functional disability preprocedurally. The adverse events were recorded using the Society of Interventional Radiology (SIR) classification.

resultsThe technical success was 100% (17/17) for a median Spinal Instability Neoplastic Score of 13.5 (interquartile range [IQR], 6.8, 20.3). Mean clinical follow-up was 10.1 months (range, 6-36 months; median, 19.5 months, IQR, 4, 35 months). Mean VAS score decreased significantly from 7.5 (SD ± 2.1) preprocedurally to 1.6 (SD ± 1.5) 24 hours postprocedurally, and 1.0 (SD ± 1.1), 1.5 (SD ± 1.0), and 0.5 (SD ± 1.5) at 1, 6, and 12 months, respectively (all P < .001). No severe adverse events were observed, but 3 cases of asymptomatic cement leakage were noted (SIR Grade 1; 17.6% [3/17]).

conclusionsLateral and posterolateral PVP performed under CT guidance and local anesthesia is safe and effective to treat symptomatic osteolytic C1-C2 lesions.

Indexed as

Anesthesia, LocalFeasibility StudiesOsteolysisRadiography, InterventionalTomography, X-Ray ComputedVertebroplastyAdultAgedAged, 80 and overBone CementsCervical VertebraeDisability EvaluationFemaleHumansMaleMiddle AgedBone Cements

Identifiers

PMID39142517
PMCPMC12832099

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.