ArticleCell2024
Schwann cell-secreted PGE
Abstract read
In one paragraph
Article in Cell, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed.
- Piezo2FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026Article
- PTBP1 knockdown reprograms glioma stem cells into neuronal-like cells and suppresses tumorigenesis via the DUSP5-ERK1/2 signaling pathway.Neuro-oncology · 2026Article
- Biohybrid cochlear implants: neural interfaces, regenerative pathways, and translational benchmarks.Journal of neuroengineering and rehabilitation · 2026Review
- Schwann cell derived extracellular vesicles are multifunctional nanotherapeutic mediators for diabetic oral mucosal wound healing.Discover nano · 2026Review
- Depletion of p75NTR in Schwann Cells Driven by Inflammation Mediates Cutaneous Pain in Psoriasis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Prostaglandin ESignal transduction and targeted therapy · 2026Article
- A bioinspired anisotropic anti-inflammatory scaffold enhances spinal nerve regeneration and neural circuit reconstruction via FGF13/CaMaterials today. Bio · 2026Article
- Injectable ROS-scavenging and NIR-responsive nanocomposite hydrogel for staphylococcus aureus-infected diabetic wound healing.Journal of nanobiotechnology · 2026Article
- Research Progress on Spinal Cord Repair Based on Regulation of the Neuroregenerative Microenvironment.Cellular and molecular neurobiology · 2026Review
- Macrophage-Derived Amphiregulin Enhances Schwann Cell Phagocytosis Through the EGFR/CTSS Signaling Pathway.Molecular neurobiology · 2026Article
- Zebrafish pou3f3b controls saccular/auditory development and marks non-neuronal cells that delaminate from the otic vesicle to promote neuroblast maturation.Developmental biology · 2026Article
- Targeting sensory nerves in the tumor microenvironment: a new vulnerability in cancer therapy.Cell communication and signaling : CCS · 2026Review
- Plasticity, injury-induced reprogramming, and translational applications of Schwann cells in neural regeneration.Frontiers in cellular neuroscience · 2026Review
- Peripheral Nerve-Cancer Interactions in the Tumor Microenvironment: A Three-Dimensional Framework Integrating Mechanisms, Modulators, and Therapeutic Strategies.Research (Washington, D.C.) · 2026Review
- Mechano-bioactive hydrogel bioelectronics for mechanical-electrical-bioenergetic conversion and glia-modulating neural regeneration.Nature communications · 2025Article
- SEMA3B switches axon-axon to axon-glia interactions required for unmyelinated axon envelopment and integrity.Nature communications · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
27 authors.
Husniye KantarciDepartment of Neurosurgery, Stanford University School of Medicine, Stanford, CA 94305, USA.
Pablo D ElviraDepartment of Chemistry, Stanford University, Stanford, CA 94305, USA.
Arun P ThottumkaraDepartment of Chemistry, Stanford University, Stanford, CA 94305, USA.
Emma M O'ConnellDepartment of Neurosurgery, Stanford University School of Medicine, Stanford, CA 94305, USA.
Manasi IyerDepartment of Neurosurgery, Stanford University School of Medicine, Stanford, CA 94305, USA.
Lauren J DonovanDepartment of Anesthesiology, Perioperative & Pain Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.
Micaela Quinn DuganDepartment of Anesthesiology, Perioperative & Pain Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.
Nicholas AmbielDepartment of Neurosurgery, Stanford University School of Medicine, Stanford, CA 94305, USA.
Alejandro GranadosChan Zuckerberg Biohub, San Francisco, CA 94158, USA.
Hong ZengTransgenic, Knockout and Tumor model Center (TKTC), Cancer Institute, Stanford University School of Medicine, Stanford, CA 94305, USA.
Nay L SawBehavioral and Functional Neuroscience Laboratory, Stanford University School of Medicine, Stanford, CA 94305, USA.
Amanda Brosius LutzDepartment of Obstetrics and Gynecology, University Hospital, Bern, Switzerland.
Steven A SloanDepartment of Human Genetics, Emory University School of Medicine, Atlanta, GA 30322, USA.
Erin E GrayDepartment of Chemistry, Stanford University, Stanford, CA 94305, USA.
Khanh V TranDepartment of Neurosurgery, Stanford University School of Medicine, Stanford, CA 94305, USA.
Aditi VichareDepartment of Neurosurgery, Stanford University School of Medicine, Stanford, CA 94305, USA.
Ashley K YehDepartment of Neurosurgery, Stanford University School of Medicine, Stanford, CA 94305, USA.
Alexandra E MünchDepartment of Neurosurgery, Stanford University School of Medicine, Stanford, CA 94305, USA.
Max HuberChan Zuckerberg Biohub, San Francisco, CA 94158, USA.
Aditi AgrawalChan Zuckerberg Biohub, San Francisco, CA 94158, USA.
Maurizio MorriChan Zuckerberg Biohub, San Francisco, CA 94158, USA.
Haining ZhongVollum Institute, Oregon Health and Science University, Portland, OR 97239, USA.
Mehrdad ShamlooDepartment of Neurosurgery, Stanford University School of Medicine, Stanford, CA 94305, USA; Behavioral and Functional Neuroscience Laboratory, Stanford University School of Medicine, Stanford, CA 94305, USA.
Thomas Anthony AndersonDepartment of Anesthesiology, Perioperative & Pain Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.
Vivianne L TawfikDepartment of Anesthesiology, Perioperative & Pain Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.
J Du BoisDepartment of Chemistry, Stanford University, Stanford, CA 94305, USA. Electronic address: jdubois@stanford.edu.
J Bradley ZucheroDepartment of Neurosurgery, Stanford University School of Medicine, Stanford, CA 94305, USA. Electronic address: zuchero@stanford.edu.
Funding
Translational Oncology Research Program (Project-005)P30CA124435 · NCI · STANFORD UNIVERSITY · PI MICHAEL KENNEY · 2007 to 2026
$71.4MTraining Program in Basic NeuroscienceT32MH020016 · NIMH · STANFORD UNIVERSITY · PI Justin L Gardner, Merritt C Maduke · 1997 to 2026
$16.2MInterdisciplinary Research Training in Pain and Substance Use DisordersT32DA035165 · NIDA · STANFORD UNIVERSITY · PI SEAN C MACKEY · 2013 to 2026
$7.2MGuanidinium Toxins as Molecular Probes for NaV StudyR01GM117263 · NIGMS · STANFORD UNIVERSITY · PI DU BOIS, JUSTIN · 2016 to 2024
$3.5MMyeloid lineage targeting to improve recovery from injury and surgery: Cellular and molecular mechanismsR35GM137906 · NIGMS · STANFORD UNIVERSITY · PI Vivianne L Tawfik · 2020 to 2026
$3.0MSensing and manipulating neuromodulatory signaling in vivoRF1MH130784 · NIMH · OREGON HEALTH & SCIENCE UNIVERSITY · PI ZHONG, HAINING · 2023 to 2023
$2.6MStanford Chem-H Chemistry/Biology Interface Predoctoral Training ProgramT32GM120007 · NIGMS · STANFORD UNIVERSITY · PI BERTOZZI, CAROLYN · 2016 to 2020
$1.2MAnimal Research Equipment, Digital Cages & Metabolic, Avoidance, Fear Conditioning, Place Preference, Self-Administration, Open Field, & Microdialysis Systems for Translational NeuroscienceS10OD030452 · OD · STANFORD UNIVERSITY · PI SHAMLOO, MEHRDAD · 2021 to 2021
$743kTransmission Electron MicroscopeS10RR026780 · NCRR · STANFORD UNIVERSITY · PI TALBOT, WILLIAM S · 2010 to 2010
$412kNCI NIH HHS P30 CA124435NCRR NIH HHS S10 RR026780NIDA NIH HHS T32 DA035165NIGMS NIH HHS R01 GM117263NIGMS NIH HHS R35 GM137906NIGMS NIH HHS T32 GM120007NIH HHS S10 OD030452NIMH NIH HHS RF1 MH130784NIMH NIH HHS T32 MH020016
Abstract
Electrical excitability-the ability to fire and propagate action potentials-is a signature feature of neurons. How neurons become excitable during development and whether excitability is an intrinsic property of neurons remain unclear. Here, we demonstrate that Schwann cells, the most abundant glia in the peripheral nervous system, promote somatosensory neuron excitability during development. We find that Schwann cells secrete prostaglandin E
Indexed as
Action PotentialsDinoprostoneSchwann CellsSensory Receptor CellsAnimalsMiceSignal TransductionDinoprostoneexcitabilityglial cellsneural developmentneuron-glia interactionsPGE2prostaglandinSchwann cellssensory behaviorsensory neuronvoltage-gated sodium channels
Identifiers
What OpenQuestion holds
Textmetadata
LicenceTDM
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.