Evidence map›Paper›PMID 39142268›Full record

ArticleImmunity2024

Challenging the role of a NOX4-Piezo1 axis in neutrophil bactericidal function.

Ulla G Knaus, Robert A Clark, William M Nauseef, Mary C Dinauer, Thomas L Leto, Vincent Jaquet

Abstract readLetterComment
In one paragraph

Article in Immunity, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. PIEZO1 in Immune Cells: From Force to Function.Results and problems in cell differentiation · 2026
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Ulla G KnausConway Institute, School of Medicine, University College Dublin, D04 V1W8 Dublin, Ireland. Electronic address: ulla.knaus@ucd.ie.
Robert A ClarkDepartment of Medicine, University of Texas Health Science Center, San Antonio, TX 78229, USA.
William M NauseefDepartment of Medicine, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA 52240, USA.
Mary C DinauerDepartment of Pediatrics, Division of Pediatric Hematology & Oncology, Washington University School of Medicine, St. Louis, MO 63110, USA.
Thomas L LetoLaboratory of Clinical Immunology & Microbiology, NIAID, NIH, Bethesda, MD 20892, USA.
Vincent JaquetDepartment of Cell Physiology & Metabolism, Centre Medical Universitaire, University of Geneva, 1211 Geneva, Switzerland.

Funding

Institute for Integration of Medicine & Science: A Partnership to Improve HealthUM1TR004538 · NCATS · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI ROBERT A CLARK, Kenneth M Hargreaves · 2023 to 2026
$22.3M
NCATS NIH HHS UM1 TR004538
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

NADPH Oxidase 4NeutrophilsAnimalsHumansMiceReactive Oxygen SpeciesNADPH Oxidase 4Reactive Oxygen Species

Identifiers

PMID39142268
PMCPMC12036669

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.