ArticleMolecular biology and evolution2024
Annelid Comparative Genomics and the Evolution of Massive Lineage-Specific Genome Rearrangement in Bilaterians.
Article in Molecular biology and evolution, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Who cites it
31 citing papers in PubMed.
- Disruption of mitonuclear coadaptation and compensatory evolution after an extreme dietary shift in carnivorous butterflies.Molecular biology and evolution · 2026Article
- Topological mixing and irreversibility in animal chromosome evolution.Science advances · 2026Article
- Chromosomal fusions shaped the genome of the greater hornwrack bryozoan (Flustra foliacea) (Linnaeus, 1758).The Journal of heredity · 2026Article
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- Brachiopod genome unveils the evolution of BMP signalling in bilaterian body patterning.Nature communications · 2026Article
- A Chromosome-level Assembly and Functional Genomic Resources for the Model Annelid Capitella teleta.Genome biology and evolution · 2026Article
- First Chromosome-level Genome Assembly and Annotation of an Endangered Freshwater Stingray (Fontitrygon garouaensis) from Africa.Scientific data · 2026Article
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- A chromosome-level assembly and functional genomic resources for the model annelidbioRxiv : the preprint server for biology · 2025Article
- Chromosome-level genome assembly of the coral grouper, Epinephelus corallicola and its evolutionary insights into Eupercaria.BMC genomics · 2025Article
- Comparative Study of Leech-Derived Tryptase Inhibitor Genes in Four Medicinal Leech Species.Biology · 2025Article
- Comparative Study of Hirudins and Encoding Genes inBiology · 2025Article
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- A phased chromosome-level genome of the annelid tubeworm Galeolaria caespitosa.The Journal of heredity · 2025Article
- Conservation of bilaterian genome structure is the exception, not the rule.Genome biology · 2025Article
- A genome resource for the marine annelid Platynereis spp.BMC genomics · 2025Article
- Genome assembly of Bougainvillia cf. muscus (Cnidaria: Hydrozoa).G3 (Bethesda, Md.) · 2025Article
- An episodic burst of massive genomic rearrangements and the origin of non-marine annelids.Nature ecology & evolution · 2025Article
- A dynamic histone-based chromatin regulatory toolkit underpins genome and developmental evolution in an invertebrate clade.Genome biology · 2025Article
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3 authors.
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Abstract
The organization of genomes into chromosomes is critical for processes such as genetic recombination, environmental adaptation, and speciation. All animals with bilateral symmetry inherited a genome structure from their last common ancestor that has been highly conserved in some taxa but seemingly unconstrained in others. However, the evolutionary forces driving these differences and the processes by which they emerge have remained largely uncharacterized. Here, we analyze genome organization across the phylum Annelida using 23 chromosome-level annelid genomes. We find that while many annelid lineages have maintained the conserved bilaterian genome structure, the Clitellata, a group containing leeches and earthworms, possesses completely scrambled genomes. We develop a rearrangement index to quantify the extent of genome structure evolution and show that, compared to the last common ancestor of bilaterians, leeches and earthworms have among the most highly rearranged genomes of any currently sampled species. We further show that bilaterian genomes can be classified into two distinct categories-high and low rearrangement-largely influenced by the presence or absence, respectively, of chromosome fission events. Our findings demonstrate that animal genome structure can be highly variable within a phylum and reveal that genome rearrangement can occur both in a gradual, stepwise fashion, or rapid, all-encompassing changes over short evolutionary timescales.
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