Evidence map›Paper›PMID 39141638›Full record

ArticlePloS one2024

The cumulative contribution of direct and indirect traumas to the production of PTSD.

Dan Even, Gregory H Cohen, Ruochen Wang, Sandro Galea

Abstract read
In one paragraph

Article in PloS one, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Different Types of Traumatic Exposure Link Divergently to PTSD and CPTSD.Stress and health : journal of the International Society for the Investigation of Stress · 2026
    Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Dan EvenMoshe Prywes Center for Medical Education, Faculty of Health Sciences, Ben Gurion University, Beer Sheva, Israel.ORCID 0000-0002-3963-0064
Gregory H CohenSchool of Public Health, Boston University, Boston, Massachusetts, United States of America.
Ruochen WangSchool of Public Health, Boston University, Boston, Massachusetts, United States of America.
Sandro GaleaSchool of Public Health, Boston University, Boston, Massachusetts, United States of America.

Funding

Optimizing Efforts to Restore Psychiatric and Social Function After a Major HurricaneR01MH119193 · NIMH · BOSTON UNIVERSITY MEDICAL CAMPUS · PI GRADUS, JAIMIE L., RUGGIERO, KENNETH J · 2020 to 2023
$2.5M
NIMH NIH HHS R01 MH119193
6 · The paper itself

Abstract

objectivePosttraumatic Stress Disorder (PTSD) affects millions of people worldwide. While the relationship between direct exposure to traumatic events and PTSD is well-established, the influence of indirect trauma exposure on PTSD remains unclear. It is similarly unclear what role cumulative exposure to direct and indirect traumas play in the risk of PTSD.

methodsThe study uses data from the Houston Trauma and Recovery Study, conducted on 2020-2021, and involved a random sampling of 1,167 individuals residing in Houston during Hurricane Harvey in 2017. Participants were asked about their experiences related to both Hurricane Harvey and the subsequent COVID-19 pandemic. Exposures were categorized as direct or indirect traumas, in line with the criteria delineated in the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5). Cumulative exposures were also calculated.

resultsAmong participants, 12.6% were experiencing current PTSD. There were significant associations between both direct [OR = 3.18, 95% CI 1.85, 5.46] and indirect [OR = 1.91, 95% CI 1.05, 3.46] traumas related to Harvey, as well as direct [OR = 2.13, 95% CI 1.20, 3.77] and indirect [OR = 1.69, 95% CI 0.93, 3.09] traumas due to COVID and the risk of PTSD in fully adjusted models. Further, significant associations were found between the cumulative exposure to traumas from both Hurricane Harvey and COVID-19 and the risk of PTSD, considering both direct [OR = 2.53, 95% CI 1.36, 4.70] and indirect exposures [OR = 2.79, 95% CI 1.47, 5.28].

conclusionsOur study offers support for connections between exposure to both direct and indirect traumas stemming from large-scale disasters and PTSD. Moreover, we show that cumulative exposures to multiple large-scale events increase the risk of PTSD. This highlights the importance of the consideration of a range of exposures as risks for PTSD, particularly in a time of compounding disasters and broad population exposures to these events.

Indexed as

COVID-19Cyclonic StormsStress Disorders, Post-TraumaticAdolescentAdultFemaleHumansMaleMiddle AgedRisk FactorsSARS-CoV-2TexasYoung Adult

Identifiers

PMID39141638
PMCPMC11324107

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.