Evidence map›Paper›PMID 39141634›Full record

ArticlePloS one2024

Availability and geographic access to breast cancer pathology services in Ghana.

Matthew D Price, Meghan E Mali, Adjei Ernest, Afua O D Abrahams, Eric Goold, Liz Elvira, Florence Dedey, Anne F Rositch, Raymond R Price, Edward K Sutherland

Abstract read
In one paragraph

Article in PloS one, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Matthew D PriceCenter for Global Surgery, The University of Utah, Salt Lake City, UT, United States of America.ORCID 0000-0003-4837-3861
Meghan E MaliCenter for Global Surgery, The University of Utah, Salt Lake City, UT, United States of America.
Adjei ErnestDepartment of Pathology, Komfo Anokye Teaching Hospital, Kumasi, Ghana.
Afua O D AbrahamsDepartment of Pathology, University of Ghana Medical School, Accra, Ghana.
Eric GooldDepartment of Pathology, The University of Utah School of Medicine, Salt Lake City, UT, United States of America.
Liz ElviraCenter for Global Surgery, The University of Utah, Salt Lake City, UT, United States of America.ORCID 0009-0007-7284-9512
Florence DedeyUniversity of Ghana Medical School, Accra, Ghana.
Anne F RositchDepartment of Epidemiology, The Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States of America.
Raymond R PriceCenter for Global Surgery, The University of Utah, Salt Lake City, UT, United States of America.
Edward K SutherlandCenter for Global Surgery, The University of Utah, Salt Lake City, UT, United States of America.ORCID 0000-0001-9304-1706

Funding

Clinical and Laboratory Research Training for Surgical OncologistsT32CA126607 · NCI · JOHNS HOPKINS UNIVERSITY · PI CAMERON, ANDREW M. · 2008 to 2024
$6.0M
NCI NIH HHS T32 CA126607
6 · The paper itself

Abstract

introductionBreast cancer poses a significant health challenge in Sub-Saharan Africa, particularly in Ghana, where late-stage diagnoses and limited healthcare access contribute to elevated mortality rates. This study focuses on the crucial role of pathology and laboratory medical (PALM) services in the timely diagnosis of breast cancer within Ghana.

methodsA cross-sectional survey of hospitals was completed from November 2020 to October 2021, with 94.8% of identified in-country hospitals participating. Pathology service-related parameters assessed included whether pathology was available for the diagnosis of breast cancer on-site or via external referral, the number of pathology personnel, additional breast cancer diagnostic capabilities including estrogen and progesterone and/or HER2 testing, and the time from biopsy to patients receiving their results. Geospatial mapping was used to identify areas of limited access.

resultsOf the 328 participating hospitals, 136 (41%) reported breast cancer pathology services, with only 6 having on-site capabilities. Pathology personnel, comprising 15 consultants and 15 specialists, were concentrated in major referral centers, particularly in Greater Accra and Kumasi. An assessment of referral patterns suggested that 75% of the population reside within an hour of breast cancer pathology services. Among the 136 hospitals with access to breast cancer pathology, only a limited number reported that results included ER/PR (38%) and HER2 testing (33%).

conclusionGhana has been able to ensure significant pathology service availability through robust referral pathways with centralized labs. Despite this, difficulties persist with the majority of pathology results not including hormone receptor testing which is important in providing tumor specific treatment.

Indexed as

Breast NeoplasmsHealth Services AccessibilityCross-Sectional StudiesFemaleGhanaHumansReferral and Consultation

Identifiers

PMID39141634
PMCPMC11324111

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.