Evidence map›Paper›PMID 39141614›Full record

ArticleHealth promotion and chronic disease prevention in Canada : research, policy and practice2024

Chronic pain and accidental acute toxicity deaths in Canada, 2016-2017.

Jeyasakthi Venugopal, Amanda VanSteelandt, Lindsey Yessick, Keltie Hamilton, Jean-François Leroux

Abstract read
In one paragraph

Article in Health promotion and chronic disease prevention in Canada : research, policy and practice, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jeyasakthi VenugopalSubstance-Related Harms Division, Health Promotion and Chronic Disease Prevention Branch, Public Health Agency of Canada, Ottawa, Ontario, Canada.
Amanda VanSteelandtSubstance-Related Harms Division, Health Promotion and Chronic Disease Prevention Branch, Public Health Agency of Canada, Ottawa, Ontario, Canada.
Lindsey YessickChronic Pain Policy Team, Controlled Substances and Cannabis Branch, Health Canada, Ottawa, Ontario, Canada.
Keltie HamiltonSubstance-Related Harms Division, Health Promotion and Chronic Disease Prevention Branch, Public Health Agency of Canada, Ottawa, Ontario, Canada.
Jean-François LerouxChronic Pain Policy Team, Controlled Substances and Cannabis Branch, Health Canada, Ottawa, Ontario, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionMultiple Canadian jurisdictions have reported a pattern of chronic pain among people who died from substance-related acute toxicity. This study examined the prevalence and characteristics of those with chronic pain using data from a national study of people who died of accidental acute toxicity.

methodsA cross-sectional analysis of accidental substance-related acute toxicity deaths that occurred in Canada between 1 January 2016 and 31 December 2017 was conducted. The prevalence of pain and pain-related conditions were summarized as counts and percentages of the overall sample. Subgroups of people with and without a documented history of chronic pain were compared across sociodemographic characteristics, health history, contextual factors and substances involved.

resultsFrom the overall sample (n = 7902), 1056 (13%) people had a history of chronic pain while 6366 (81%) had no documented history. Those with chronic pain tended to be older (40 years and older), unemployed, retired and/or receiving disability supports around the time of death. History of mental health conditions, trauma and surgery or injury was significantly more prevalent among people with chronic pain. Of the substances that most frequently contributed to death, opioids typically prescribed for pain (hydromorphone and oxycodone) were detected in toxicology more often among those with chronic pain than those without.

conclusionFindings underscore the cross-cutting role of multiple comorbidities and unmanaged pain, which could compound the risk of acute toxicity death. Continued prioritization of harm reduction and regular patient engagement to assess ongoing needs are among the various opportunities for intervention.

Indexed as

Chronic PainAdolescentAdultAgedAge FactorsAnalgesics, OpioidCanadaCross-Sectional StudiesDrug OverdoseFemaleHumansMaleMiddle AgedPrevalenceSociodemographic FactorsYoung AdultAnalgesics, Opioidacute toxicitychronic paincontrolled substancesdrug overdoseopioid crisisopioid overdosesubstance-related disorderssubstance use

Identifiers

PMID39141614
PMCPMC11498322

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.