Evidence map›Paper›PMID 39141476›Full record

ArticleIEEE transactions on bio-medical engineering2025

Computationally Efficient Implicit Training Strategy for Unrolled Networks (IMUNNE): A Preliminary Analysis Using Accelerated Real-Time Cardiac Cine MRI.

Nikolay Iakovlev, Florian A Schiffers, Santiago L Tapia, Daming Shen, KyungPyo Hong, Michael Markl, Daniel C Lee, Aggelos K Katsaggelos, Daniel Kim

Abstract read
In one paragraph

Article in IEEE transactions on bio-medical engineering, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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2 · The registry

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Nikolay Iakovlev
Florian A Schiffers
Santiago L Tapia
Daming Shen
KyungPyo Hong
Michael Markl
Daniel C Lee
Aggelos K Katsaggelos
Daniel Kim

Funding

Comprehensive Cardiac Structure-Function Analysis in Heart TransplantationR01HL117888 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI CARR, JAMES, MARKL, MICHAEL · 2014 to 2025
$6.4M
Precision MRI of Left Atrial Fibrosis for Patients with Atrial FibrillationR01HL116895 · NHLBI · UNIVERSITY OF UTAH · PI KIM, DANIEL · 2014 to 2025
$5.1M
Wideband 3D LGE and Coronary MRA for Planning Ventricular Tachycardia AblationR01HL151079 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Daniel Kim, Daniel Ching-Hao Lee · 2020 to 2026
$4.0M
Quantitative Detection of Coronary Microvascular Dysfunction in Long COVID Patients using a Comprehensive, Rapid, Free-Breathing Cardiovascular MRIR01HL167148 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Daniel Kim, Daniel Ching-Hao Lee · 2023 to 2026
$3.1M
Safe and Effective MRI for Pediatric Patients with a Cardiac Implantable Electronic DeviceR01HL168859 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Laleh Golestani Rad, Daniel Kim · 2024 to 2026
$2.0M
Rapid Real-Time Cardiovascular MRI for Detecting Coronary Artery DiseaseR01HL138578 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI KIM, DANIEL, LEE, DANIEL CHING-HAO · 2017 to 2019
$1.1M
American Heart Association-American Stroke Association 949899NHLBI NIH HHS R01 HL116895NHLBI NIH HHS R01 HL117888NHLBI NIH HHS R01 HL138578NHLBI NIH HHS R01 HL151079NHLBI NIH HHS R01 HL167148NHLBI NIH HHS R01 HL168859
6 · The paper itself

Abstract

objectiveHighly-undersampled, dynamic MRI reconstruction, particularly in multi-coil scenarios, is a challenging inverse problem. Unrolled networks achieve state-of-the-art performance in MRI reconstruction but suffer from long training times and extensive GPU memory cost.

methodsIn this work, we propose a novel training strategy for IMplicit UNrolled NEtworks (IMUNNE) for highly-undersampled, multi-coil dynamic MRI reconstruction. It formulates the MRI reconstruction problem as an implicit fixed-point equation and leverages gradient approximation for backpropagation, enabling training of deep architectures with fixed memory cost. This study represents the first application of implicit network theory in the context of real-time cine MRI. The proposed method is evaluated using a prospectively undersampled, real-time cine dataset using radial k-space sampling, comprising balanced steady-state free precession (b-SSFP) readouts. Experiments include a hyperparameter search, head-to-head comparisons with a complex U-Net (CU-Net) and an alternating unrolled network (Alt-UN), and an analysis of robustness under noise perturbations; peak signal-to-noise ratio, structural similarity index, normalized root mean-square error, spatio-temporal entropic difference, and a blur metric were used.

resultsIMUNNE produced significantly and slightly better image quality compared to CU-Net and Alt-UN, respectively. Compared with Alt-UN, IMUNNE significantly reduced training and inference times, making it a promising approach for highly-accelerated, multi-coil real-time cine MRI reconstruction.

conclusionIMUNNE strategy successfully applies unrolled networks to image reconstruction of highly-accelerated, real-time radial cine MRI. SIGNIFICANCE: Implicit training enables rapid, high-quality, and cost-effective CMR exams by reducing training and inference times and lowering memory cost associated with advanced reconstruction methods.

Indexed as

HeartImage Processing, Computer-AssistedMagnetic Resonance Imaging, CineNeural Networks, ComputerAlgorithmsDeep LearningHumans

Identifiers

PMID39141476
PMCPMC11825888

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.