Evidence map›Paper›PMID 39141413›Full record

ArticleTransactions of the Royal Society of Tropical Medicine and Hygiene2024

Podoconiosis in Uganda: prevalence, geographical distribution and risk factors.

Ivan Masete, Hope Simpson, Gabriel Matwale, Francis Mutebi, Marlene Thielecke, Fred Nuwaha, George Mukone, Kebede Deribe, Gail Davey

Erratum issuedAbstract read
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In one paragraph

Article in Transactions of the Royal Society of Tropical Medicine and Hygiene, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Ivan MaseteResearch Department, Innovations for Tropical Disease Elimination, Mukono, P.O. Box 24461, Kampala, Uganda.ORCID 0009-0009-3389-0226
Hope SimpsonDepartment of Global Health and Infection, Brighton and Sussex Medical School, 94 N - S Rd, Falmer, Brighton, BN1 9PX, UK.
Gabriel MatwaleVector-borne and Neglected Tropical Diseases Division, Ministry of Health, P.O. Box 1661, Kampala, Uganda.
Francis MutebiCollege of Veterinary Medicine, Animal Resources and Biosecurity, Makerere University, P.O. Box 7062, Kampala, Uganda.
Marlene ThieleckeCharité Center for Global Health, Institute of International Health, Charité University Medicine, 13353 Berlin, Germany.
Fred NuwahaDepartment of Disease Control and Environmental Health, Makerere University School of Public Health, P.O. Box 7062, Kampala, Uganda.
George MukoneResearch Department, Innovations for Tropical Disease Elimination, Mukono, P.O. Box 24461, Kampala, Uganda.
Kebede DeribeDepartment of Global Health and Infection, Brighton and Sussex Medical School, 94 N - S Rd, Falmer, Brighton, BN1 9PX, UK.
Gail DaveyDepartment of Global Health and Infection, Brighton and Sussex Medical School, 94 N - S Rd, Falmer, Brighton, BN1 9PX, UK.ORCID 0000-0003-2796-7468

Funding

Wellcome TrustWellcome Trust 201-900/Z/16/Z
6 · The paper itself

Abstract

backgroundPodoconiosis is a neglected debilitating yet preventable disease. Despite its public health significance, podoconiosis is often misdiagnosed and confused with lymphatic filariasis. No appropriate diagnostic tests exist, contributing to underestimation and the absence of control interventions.

methodsA population-based cross-sectional survey was conducted in seven districts with suspected or reported cases of podoconiosis or an altitude of 1200 m above sea level. Conducted from 30 January to 19 March 2023, the survey employed multilevel stratified sampling to reach eligible household members.

resultsOf the 10 023 participants sampled, 187 (confidence interval 1.25 to 2.78) had clinical features of podoconiosis. The highest prevalence was recorded in Nakapiripirit (7.2% [58/809]) and Sironko (2.8 [44/1564]) and the lowest in Kasese (0.3% [5/1537]), but ranged from 1.1 to 1.8% in Zombo, Rukungiri, Gomba and Hoima districts. The duration of podoconiosis was reported to range from 1 to 57 y. Factors associated with podoconiosis occurrence included advanced age, tungiasis, household cleanliness and personal hygiene. Sleeping on a bed, bathing daily, use of soap and use of footwear in at least moderate condition were protective against podoconiosis.

conclusionsPodoconiosis occurred in all the sampled districts and was linked to personal hygiene. Long-standing cases suggest an absence of treatment. There is potential for early intervention using a holistic care model in managing this condition. Urgent action and stakeholder engagement are essential for effective podoconiosis management.

Indexed as

ElephantiasisAdolescentAdultAgedChildChild, PreschoolCross-Sectional StudiesFemaleHumansHygieneMaleMiddle AgedPrevalenceRisk FactorsShoesTungiasislymphoedemaneglected tropical diseasespodoconiosisprevalencerisk factors

Identifiers

PMID39141413
PMCPMC11637681

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.