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ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2024

Barriers to and facilitators of improving physical activity and nutrition behaviors during chemotherapy for breast cancer: a sequential mixed methods study.

Leah S Puklin, Melinda L Irwin, Tara Sanft, Leah M Ferrucci, Maura Harrigan, Courtney McGowan, Brenda Cartmel, Michelle Zupa, Eric P Winer, Maryann Deyling and 4 more

Abstract read
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In one paragraph

Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. What helps or hinders adult cancer patients in accepting dietary interventions during chemotherapy? A qualitative synthesis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Pooled it
  2. Pooled it
  3. Trial
  4. Food group intake and chemotherapy-induced toxicity: a scoping review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  5. Effects of a clinic-referred telemedical intervention to improve exercise uptake during chemotherapy.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Leah S PuklinYale School of Public Health, Yale University, 47 College St., New Haven, CT, 06510, USA. leah.puklin@yale.edu.
Melinda L IrwinYale School of Public Health, Yale University, 47 College St., New Haven, CT, 06510, USA.
Tara SanftYale Cancer Center, New Haven, CT, 06510, USA.
Leah M FerrucciYale School of Public Health, Yale University, 47 College St., New Haven, CT, 06510, USA.
Maura HarriganYale School of Public Health, Yale University, 47 College St., New Haven, CT, 06510, USA.
Courtney McGowanYale Cancer Center, New Haven, CT, 06510, USA.
Brenda CartmelYale School of Public Health, Yale University, 47 College St., New Haven, CT, 06510, USA.
Michelle ZupaYale Cancer Center, New Haven, CT, 06510, USA.
Eric P WinerYale Cancer Center, New Haven, CT, 06510, USA.
Maryann DeylingYale School of Public Health, Yale University, 47 College St., New Haven, CT, 06510, USA.
Jennifer A LigibelDana Farber Cancer Institute, Boston, MA, USA.
Karen Basen-EngquistCenter for Energy Balance, Department of Behavioral Science, MD Anderson Cancer Center, Houston, TX, 77030, USA.
Donna SpiegelmanYale School of Public Health, Yale University, 47 College St., New Haven, CT, 06510, USA.
Mona SharifiYale School of Public Health, Yale University, 47 College St., New Haven, CT, 06510, USA.

Funding

NRSA Training CoreTL1TR001864 · NCATS · YALE UNIVERSITY · PI CANTLEY, LLOYD G, EDELMAN, E. JENNIFER · 2016 to 2025
$9.9M
Dissemination and Implementation of the Bright Bodies Intervention for Childhood ObesityR01HL151603 · NHLBI · YALE UNIVERSITY · PI Mahnoosh Sharifi · 2020 to 2026
$4.7M
Implementation of Decision Support for the Management of Obesity in a National Pediatric Primary Care Research NetworkR01MD014853 · NIMHD · YALE UNIVERSITY · PI SHARIFI, MAHNOOSH · 2020 to 2024
$3.9M
A randomized trial of lifestyle guidelines on breast cancer biomarkers and treatment adherenceR01CA207753 · NCI · YALE UNIVERSITY · PI IRWIN, MELINDA L, SANFT, TARA B · 2017 to 2021
$3.5M
Transdisciplinary Research in Energetics and Cancer (TREC) Training GrantR25CA203650 · NCI · YALE UNIVERSITY · PI IRWIN, MELINDA L · 2016 to 2025
$2.9M
Bridging the Gap: Evaluating why and how to implement lifestyle programs for cancer patients into routine clinical oncology careF31CA268894 · NCI · YALE UNIVERSITY · PI PUKLIN, LEAH · 2022 to 2023
$72k
NCATS NIH HHS TR001864NCI NIH HHS 5R01CA207753NCI NIH HHS F31CA268894NCI NIH HHS R25CA203650NHLBI NIH HHS R01 HL151603NHLBI NIH HHS R01HL151603NIMHD NIH HHS R01 MD014853NIMHD NIH HHS R01MD014853
6 · The paper itself

Abstract

purposeUse qualitative and quantitative methods to explore factors influencing the adoption of guideline-based physical activity (PA) and dietary recommendations among participants enrolled in a lifestyle intervention during and after chemotherapy for breast cancer.

methodsAmong women with stage I-III breast cancer who participated in the intervention arm of the Lifestyle, Exercise, and Nutrition early after diagnosis (LEANer) trial, we used stratified, purposeful sampling to interview women who met both, one, or neither intervention goal after the 1-year intervention: (1) 150 min/week moderate-to-vigorous intensity exercise via a self-reported PA questionnaire and (2) improved self-reported diet quality measured by the Healthy Eating Index-2015. Semi-structured interviews were audio-recorded, transcribed verbatim, and analyzed using thematic content analysis.

resultsThe 29 women interviewed were 52 ± 11 years old on average, with a mean body mass index of 29.6 ± 7.7 kg/m

conclusionsWomen reported the external support, tailored education, and experiencing the physical and mental benefits of the LEANer intervention facilitated the adoption of the interventions' behavioral goals. Addressing chemotherapy-related symptoms and competing priorities may facilitate adherence to lifestyle interventions during chemotherapy for breast cancer.

Indexed as

Breast NeoplasmsExerciseAdultAgedAntineoplastic AgentsFemaleHealth BehaviorHumansLife StyleMiddle AgedQualitative ResearchSurveys and QuestionnairesAntineoplastic AgentsBreast cancerChemotherapyDiet qualityExerciseLifestyle interventionMixed methodsPhysical activity

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.