Evidence map›Paper›PMID 39141175›Full record

ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2024

Validation of the EQ-5D-Y-5L parent-proxy version among children with juvenile idiopathic arthritis.

Arto Ohinmaa, Jiabi Wen, Gillian R Currie, Susanne M Benseler, Joost F Swart, Sebastiaan J Vastert, Rae S M Yeung, Deborah A Marshall

Abstract readValidation Study
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Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

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5citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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5 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Arto OhinmaaSchool of Public Health, University of Alberta, Edmonton, Canada.
Jiabi WenSchool of Public Health, University of Alberta, Edmonton, Canada.
Gillian R CurrieDepartment of Paediatrics, Cumming School of Medicine, University of Calgary, Calgary, Canada. currie@ucalgary.ca.ORCID http://orcid.org/0000-0002-4681-9893
Susanne M BenselerAlberta Children's Hospital Research Institute, University of Calgary, Calgary, Canada.
Joost F SwartDepartment of Pediatric Immunology and Rheumatology, Wilhelmina Children's Hospital / UMC Utrecht and University of Utrecht, Utrecht, The Netherlands.
Sebastiaan J VastertDepartment of Pediatric Immunology and Rheumatology, Wilhelmina Children's Hospital / UMC Utrecht and University of Utrecht, Utrecht, The Netherlands.
Rae S M YeungDepartment of Paediatrics, Immunology and Medical Science, The Hospital for Sick Children, University of Toronto, Toronto, Canada.
Deborah A MarshallDepartment of Community Health Sciences, Cumming School of Medicine, University of Calgary, Calgary, Canada.

Funding

Arthritis Society SOG18-0253
6 · The paper itself

Abstract

objectivesJuvenile idiopathic arthritis (JIA) is the most common type of arthritis among children. It can cause joint pain and permanent physical damage, which affects mobility and daily activities. The EQ-5D-Y-3L self-report version has been validated in JIA, but the validity of EQ-5D-Y-5L remains unknown. We examined the psychometric properties of the EQ-5D-Y-5L parent-proxy version among children with JIA.

methodsWe used data from the Understanding Childhood Arthritis Network Canadian-Dutch collaboration study cohort, including patients with new-onset JIA, and those starting or stopping biologics. Clinical data and the parent-proxy version of the childhood health assessment questionnaire (CHAQ) and EQ-5D-Y-5L were collected. We evaluated the ceiling and floor effect; convergent and divergent validity using Spearman's rank correlation; known-group validity using one-way ANOVA (Analysis of Variance) and effect size; and informativity using Shannon's evenness index.

results467 patient visits representing 407 patients were analyzed. The EQ-5D-Y-5L had no ceiling/floor effect. The EQ-5D-Y-5L showed good convergent (e.g., EQ-5D-Y-5L pain/discomfort dimension vs. CHAQ pain index (Spearman's r = 0.74, 95% confidence interval (C.I.): 0.69-0.79)), divergent (e.g., EQ-5D-Y-5L pain/discomfort dimension vs. CHAQ eating dimension (Spearman's r = 0.19, 95% C.I.: 0.09-0.29)) and known-group validity (e.g., mean EQ-5D-Y-5L level summary score for patients with inactive versus active disease status, 6.34 vs. 10.52 (p < 0.001, effect size = 1.20 (95% C.I.: 0.95-1.45)). Shannon's evenness index ranged from 0.52 to 0.88, suggesting most dimensions had relatively even distributions.

conclusionsIn this patient sample, EQ-5D-Y-5L parent-proxy version exhibited construct validity and informativity, suggesting the EQ-5D-Y-5L can be used to measure the quality of life of children with JIA.

Indexed as

Arthritis, JuvenileParentsPsychometricsQuality of LifeAdolescentCanadaChildChild, PreschoolFemaleHumansMaleNetherlandsProxyReproducibility of ResultsSurveys and QuestionnairesEQ-5D-Y-5LHealth-related quality of lifeJuvenile idiopathic arthritisPatient-reported outcome measurePsychometric propertiesValidity

Identifiers

PMID39141175
PMCPMC11452410

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.