Evidence map›Paper›PMID 39141143›Full record

ArticleLasers in medical science2024

Laser-induced optical breakdown is a prior strategy for acquired melanin-increased disorder in dermal layer.

Yun-Jhen Lin, Bing-Qi Wu, Chang-Cheng Chang, Yung-Hsueh Huang, Yen-Jen Wang

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In one paragraph

Article in Lasers in medical science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yun-Jhen LinChina Medical University, Medicine, No.91 Hsueh-Shih Road, Taichung, TW, Taiwan.
Bing-Qi WuChina Medical University, Medicine, No.91 Hsueh-Shih Road, Taichung, TW, Taiwan.
Chang-Cheng ChangDepartment of Plastic Surgery, China Medical University Hospital, No2 Yuder Rd, Taichung, TW, Taiwan. changcc1975@gmail.com.ORCID http://orcid.org/0000-0002-0463-7346
Yung-Hsueh HuangDepartment of Cosmetology, Yung-Hsueh Huang Dermatology Clinic, Changhua, TW, Taiwan.
Yen-Jen WangMackay Memorial Hospital, Dermatology, No. 92, Sec. 2, Zhongshan N. Rd, Taipei, TW, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This brief report discusses the challenges in treating dermal melanosis and the limitations of current laser treatments due to inadequate tissue penetration and potential side effects. It introduces laser-induced optical breakdown (LIOB) as a novel therapeutic approach using a picosecond laser with a diffractive lens array (DLA) to target dermal pigmentation effectively. LIOB induces multiphoton ionization, leading to melanin clearance through phagocytosis and apoptotic cell removal, while also promoting dermal remodeling and collagen synthesis. We present a case of successful treatment of dermal pigmentation in a 55-year-old woman using 755 nm-picosecond alexandrite laser therapy, demonstrating significant improvement without recurrence. The findings suggest that LIOB offers a promising solution for acquired dermal hypermelanosis by addressing both diffuse and localized pigmentation effectively, leading to skin rejuvenation with minimal downtime and high patient satisfaction.

Indexed as

Lasers, Solid-StateFemaleHumansLow-Level Light TherapyMelaninsMelanosisMiddle AgedRejuvenationMelaninsAcquired hypermelanosisDermal hyperpigmentationLaser-induced optical breakdownPicosecond laser

Identifiers

PMID39141143

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.