Evidence map›Paper›PMID 39141132›Full record

ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2025

Usefulness of pre- and post-treatment volumetric PET/CT parameters in predicting prognosis and evaluating recurrence for chemoradiotherapy-treated hypopharyngeal cancer.

Eiichiro Okazaki, Koichi Koyama, Masahiko Higashikawa, Norifumi Nishida, Haruyuki Fukuda

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Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Eiichiro OkazakiDepartment of Radiation Oncology, Saiseikai Nakatsu Hospital, 2-10-39 Shibata, Kita-ku, 530-0012, Osaka, Japan. eiichiro.ok@gmail.com.ORCID http://orcid.org/0000-0002-8489-8668
Koichi KoyamaPET Center, Saiseikai Nakatsu Hospital, Osaka, Japan.
Masahiko HigashikawaDepartment of Otolaryngology, Saiseikai Nakatsu Hospital, Osaka, Japan.
Norifumi NishidaDepartment of Diagnostic Radiology, Saiseikai Nakatsu Hospital, Osaka, Japan.
Haruyuki FukudaDepartment of Radiation Oncology, Saiseikai Nakatsu Hospital, 2-10-39 Shibata, Kita-ku, 530-0012, Osaka, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the usefulness of pre- and post-treatment metabolic tumor volume (MTV) obtained from positron emission tomography (PET) in predicting prognosis and evaluating recurrence in patients with hypopharyngeal cancer (HPC). MATERIALS AND

methodsForty-three consecutive HPC patients treated with chemoradiotherapy were retrospectively analyzed. Maximum standard uptake value (SUVmax) and MTV of tumor (T) and lymph node (N) were analyzed.

resultsOn multivariate analysis using pre-treatment parameters, MTV-T (p = 0.049) and MTV-TN (p = 0.043) were significantly associated with local control (LC), and MTV-N (p = 0.049) was significantly associated with disease-specific survival (DSS). Post-treatment MTV-TN was also significantly associated with prognosis (p < 0.001 in LC; p = 0.002 in DSS) and recurrence (area under curve 0.95). Neither pre- nor post-treatment SUVmax was significantly associated with prognosis.

conclusionPre- and post-treatment MTV appears useful for predicting prognosis and evaluating recurrence.

Indexed as

Carcinoma, Squamous CellChemoradiotherapyHypopharyngeal NeoplasmsNeoplasm Recurrence, LocalPositron Emission Tomography Computed TomographyAdultAgedFemaleHumansMaleMiddle AgedPrognosisRetrospective StudiesTumor BurdenConcurrent chemoradiotherapyHypopharyngealMetabolic tumor volumePETRadiotherapy

Identifiers

PMID39141132

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.